Results 111 to 120 of about 334,030 (336)

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

The Use of Herbal Medicine in Children of Birjand City, Iran

open access: yesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2015
Background and Objectives: In recent years, the use of herbal medicine is increasing in different countries of the world. In this study, the use of herbal medicine in children and its related factors were investigated in Birjand city.
Azita Fesharakinia
doaj  

Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?

open access: yesMolecular Oncology, EarlyView.
Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley   +1 more source

The benefits of hypnosis as an adjunct treatment for bronchial asthma–a clinical trial

open access: yesMedisan
Introduction: Bronchial asthma is a prevalent chronic respiratory disease associated with significant morbidity and healthcare costs. Complementary and alternative therapies, including hypnosis, have gained interest as potential adjunct treatments for ...
Yaimarelis Picó Carela   +4 more
doaj  

Responses of Diabetes Mellitus Patients Who Used Complementary Medicine [PDF]

open access: yes, 2016
Diabetes Mellitus as a chronic disease tend to seek appropriate medical treatment to heal the condition. Health-seek searched can be either medical treatment or Complementary and Alternative Medicine.
Agil, M. (Mangestuti)   +4 more
core  

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

open access: yesMolecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma   +9 more
wiley   +1 more source

“Complement-ary” Therapies for Age-Related Macular Degeneration

open access: yesOphthalmology Science, 2022
Jonathan B. Lin, MD, PhD   +1 more
doaj   +1 more source

The local evaluation of Knutsford’s Healthy Living Network: January 2006 – December 2006

open access: yes, 2007
This was an exploratory study designed to evaluate the Knutsford Healthy Living Network (KHLN), one of many Healthy Living Centres (HLC) in the UK. The HLC initiative aims to ensure people can achieve their optimum state of health and well-being.
Alford, Simon, Perry, Catherine
core  

Evolution and Complementarity? Traditional and Complementary Medicine as Part of the International Human Rights Law Right to Health [PDF]

open access: yes, 2020
In International Human Rights Law, the International Covenant on Economic, Social and Cultural Rights defines the right to health as the right of everyone to the enjoyment of the highest attainable standard of physical and mental health.
Carne, Greg, Doolan, Angela
core  

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

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