Results 91 to 100 of about 353,350 (303)
Background: Type 2 diabetes mellitus (T2DM) has primarily been managed with modern medicine, which is often target-based and nonholistic, leading to long-term adverse effects.
Akshay Vashisht +2 more
doaj +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Alternative healing as a complement to traditional, western therapy [PDF]
Plan BThe purpose of this research is to investigate the current status of Wisconsin mental health professionals’ opinions, knowledge, and experiences regarding alternative modes of healing in conjunction with Western therapy.
Bates, Nora
core
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
How Do We Know It Works? Approaches to the Evaluation of Complementary Medicine
Complementary medicine is a term used to cover a vast array of treatment procedures as wide ranging as aroma therapy, iridology, acupuncture, homeopathy and osteopathy. It is sometimes known as alternative or even folk medicine.
Canter, David V.
core
A systematic review of guided imagery as an adjuvant cancer therapy
Aim: The aim of this paper is to summarise and critically evaluate the evidence available from controlled clinical trials regarding the use of guided imagery as a sole adjuvant therapy for cancer patients.
Roffe, L., Ernst, E., Schmidt, K.
core +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
This systematic review critically appraises the role of complementary and alternative medicine in the treatment of those with an eating disorder. Sixteen studies were included in the review.
Hay, Phillipa (R12066) +2 more
core +1 more source

