Results 111 to 120 of about 353,350 (303)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Exploring Chronic Pain Management Experiences and the Use of Complementary Therapies Among Hemodialysis Patients: A Qualitative Study

Journal of Pubnursing Sciences
Background: Chronic pain is a common and distressing experience for patients with end-stage renal disease (ESRD) undergoing hemodialysis, yet its complexity and management remain insufficiently explored.
Imelda Rahmayunia Kartika, Fitrianola Rezkiki   +1 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Impact of Complementary Therapy on PTSD Symptoms

, 2020
Post-Traumatic Stress Disorder (PTSD) is a mental health condition individuals of any age may develop after exposure to one or multiple threatening events; such events may include experiences of war, witnessing a violent death, sexual or physical ...
Gaber, Natalie, Buckner, Allison
core  

Practice guidelines for acupuncturists using acupuncture as an adjunctive treatment for anorexia nervosa

, 2015
Anorexia nervosa is a potentially life-threatening eating disorder where people intentionally refuse to eat sufficient amounts to maintain a healthy body-weight for fear of becoming fat.
Ramjan, Lucie M. (R13951), Fogarty, Sarah (R16673)   +1 more
core   +1 more source

Literature Review: Cranberry in Preventive Medicine—A Herbal Approach to Recurrent Urinary Tract Infections

Proceedings
Introduction: Urinary tract infections (UTIs) represent a growing health challenge, due to the rise of antimicrobial resistance (AMR) in common pathogens.
Hizza K. B. Rocha, Lais J. Capistrano, Maria L. S. Almeida   +2 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

The Effect of Foot Reflexology on Sleep Quality in Patients With Chronic Lymphocytic Leukemia Under Chemotherapy: A Randomized Controlled Trial

Health Science Reports
Background and Aims Chronic lymphocytic leukemia (CLL) frequently causes a range of physical and psychological symptoms, including disrupted sleep. Foot reflexology is thought to promote relaxation and improve sleep quality.
Naser Parizad, Amireh Hassanpour, Rasoul Goli, Hamidreza Khalkhali, Aysan Nozad   +4 more
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Cancer Patients’ Behavior and Perception on the Use of Medical Foods and Dietary Supplements During Chemotherapy

Patient Preference and Adherence
Danupol Chavengkijsakol,1 Jirayut Kongjan,1 Thanapoom Suwanwattanakul,1 Bussaba Trakarnsanga,2 Nutthada Areepium,3 Tippawan Siritientong1,4 1Department of Food and Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences, Chulalongkorn University ...
Chavengkijsakol D, Kongjan J, Suwanwattanakul T, Trakarnsanga B, Areepium N, Siritientong T   +5 more
doaj