Results 191 to 200 of about 177,591 (297)

A sensitive interactome-based approach to characterize drug activity in living human cells. [PDF]

J Biol Chem
Kundlacz C, Forcet C, Sleiman NH, Vonau S, Marmigère F, Gillet B, Hughes S, Gilquin L, Duplus H, Dumont A, Yvert G, Bleicher F, Gautier A, Coste I, Renno T, Merabet S.   +15 more
europepmc   +1 more source

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

FEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley, Luke W. Molesworth, Nethma H. Waduge, Fahimeh Eskandari, Peter R. Boag, Gregory M. Davis   +5 more
wiley   +1 more source

Defining the order of assembly of the <i>Clostridioides difficile</i> divisome complex. [PDF]

J Bacteriol
Harrison GA, Kuhn P, Shrestha S, Caballero Blanco P, Havey L, Shen A.   +5 more
europepmc   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

<i>MaMHR</i> Contributes to Conidiation, Stress Adaptation, and Virulence in <i>Metarhizium acridum</i>. [PDF]

J Fungi (Basel)
Li G, Li K, Xia Y.
europepmc   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

Correction: Transporter NRT1.5/NPF7.3 suppresses primary root growth under low K+ stress by regulating the degradation of PIN-FORMED2. [PDF]

BMC Plant Biol
Wang Y, Wang R, Zhao S, Lu C, Zhu Z, Li H.   +5 more
europepmc   +1 more source

Leucine auxotrophic marker for genetic manipulation of <i>Mycobacterium abscessus</i>. [PDF]

Appl Environ Microbiol
Griesser T, Selchow P, Sander P.
europepmc   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

VdPRMT1 Is Required for Fungal Growth, Metabolism, and Pathogenicity in <i>Verticillium dahliae</i>. [PDF]

Cells
Li W, Li S, Wu S, Jin X, Guo H, Cheng H, Li Y, Guo W, Su X.   +8 more
europepmc   +1 more source