Results 31 to 40 of about 2,888 (202)
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Robust Image Encryption with 2D Hyperchaotic Map and Dynamic DNA-Zigzag Encoding
EntropyThis study presents a novel two-dimensional hyperchaotic map, referred to as the 2D exponent-logarithm-sine chaotic map (2D-ELSCM), which is intricately designed through the interplay of exponential, logarithmic, and sine functions.
Haijun Zhang +4 more
doaj +1 more source
Permutation groups of prime power degree and $p$-complements
Trudy Instituta Matematiki i Mekhaniki UrO RANExtending earlier work of Guralnick and of Cai and Zhang, we classify the almost simple groups which have transitive permutation representations of prime power degree $p^k$, and those which have $p$-complements (stabilisers of order coprime to $p$ in such representations).
Jones, Gareth A., Sezer, Sezgin
openaire +2 more sources
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Alterations in cortical surface morphometry in fibromyalgia: a multi-parametric study
Frontiers in PsychologyIntroductionFibromyalgia (FM) is a chronic pain disorder with unclear neuroanatomical basis, as previous studies largely relied on volumetric measures insensitive to cortical surface morphology.
Jiancheng Hou +2 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Portugaliae MathematicaLet G be a simple graph and k\in\mathbb{N} . Two important graph operations are: the k
Margarida Cleto +2 more
openaire +1 more source