Results 111 to 120 of about 294,344 (225)

Emergence of So as Complementizer in Chinese Pidgin English

open access: yes, 2013
This study examines the development of so as a complementizer in Chinese Pidgin English. When used lexically, so almost always occurs in the expression so fashion ‘in this way’ which can be used as a predicate, a manner deictic and a conjunction ...
Li, KLM
core  

Grtp1 Safeguards Against Paternal Reproductive Aging and Intergenerational Behavioral Deficits by Preserving Redox Homeostasis

open access: yesAdvanced Science, EarlyView.
This study identifies that Grtp1 maintains germline redox homeostasis by interacting with PRDX1/4‐TXN to antagonize paternal reproductive aging. Growth hormone restores Grtp1 expression, rectifies aberrant sperm DNA methylation, and ameliorates intergenerational anxiety and social deficits, highlighting the GH‐GRTP1 axis as a promising intervention ...
Yingdong Liu   +23 more
wiley   +1 more source

Multi‐Technique Integration Identifies O‐GlcNAc Transferase in Fibroblast‐Like Synoviocytes as a Therapeutic Target for Rheumatoid Arthritis

open access: yesAdvanced Science, EarlyView.
AI‑guided single‑cell transcriptomics identifies OGT as a key regulator enriched in rheumatoid arthritis fibroblast‑like synoviocytes (RA‐FLSs). Inflammatory stimuli activate the OGT–SAP130 axis, which modulates the H3K27ac/H3K27me3 balance and epigenetically silences BTG2, promoting aggressive transformation of RA‑FLSs.
Duoli Xie   +14 more
wiley   +1 more source

Light Verb Complement Deletion in Japanese and Phase Complement Ellipsis [PDF]

open access: yes
This paper argues that Japanese owns VP ellipsis observed in British English (do complement ellipsis, Light verb complement deletion) in terms of apparent VP ellipsis (VP ellipsis with a particle) and Sino-Japanese VP ellipsis. Apparent VP ellipsis cannnot be captured by vP ellipsis in English (Fujii 2016, Funakoshi 2020) and argument ellipsis ...
openaire  

Glucose and Glutamine Deprivation Promotes Breast Cancer Lung Metastasis via BRD4‐Dependent Enhancer Activation

open access: yesAdvanced Science, EarlyView.
To model a nutrient‐restricted tumor microenvironment, breast cancer cells were adapted to low glucose and glutamine levels. In the adapted cells, BRD4‐driven enhancer activation increases pro‐invasive EDN1 expression, facilitated by ATF3/c‐JUN and reinforced by enhancer RNA.
Poshan Yugal Bhattarai   +4 more
wiley   +1 more source

More on Complementizer Deletion Phenomena in English

open access: yesMore on Complementizer Deletion Phenomena in English
0. Introduction / 1. Distributional Circumstance in That -deletion / 1.1. Facts and Problems / 1.2. ECP account / 1.3. Nakamura's Analysis / 2.0. A New Analysis / 2.1. Appositive Clause / 2.2 Verbs of Manner of Speaking / 3.
openaire   +1 more source

Reversing Macrophage Immunometabolic Dysfunction in Prolonged Infections Via a Glutaminolysis‐Fueled Restoration‐Based Hierarchically Selective Therapeutic System

open access: yesAdvanced Science, EarlyView.
A hierarchically selective immunotherapeutic nanoplatform, mGls@HEV‐MTP, selectively restores macrophage immunocompetence through GLS1‐mediated restoration of glutaminolysis‐fueled anaplerosis. Concurrently, it renders Staphylococcus aureus (S. aureus) more readily recognizable to the metabolically reprogrammed macrophages, thereby facilitating ...
Weinan Yang   +17 more
wiley   +1 more source

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