Results 121 to 130 of about 294,344 (225)

(Not) Hearing Optional Subjects: The Effects of Pragmatic Usage Preferences. [PDF]

J Mem Lang, 2012
Mack JE, Clifton C, Frazier L, Taylor PV.   +3 more
europepmc   +1 more source

MethyAnno: An Interpretable Automated Annotation Method Leveraging Multi‐Scale Information and Metric Learning Framework for scDNAm Data

Advanced Science, EarlyView.
MethyAnno enables robust and interpretable annotation of single‐cell DNA methylation data by integrating multi‐scale epigenetic information, bidirectional cross‐attention, and prototype‐based metric learning. The framework resolves rare and novel cell types across datasets while revealing cell‐type‐specific epigenetic signatures associated with disease
Yuhang Jia, Siyu Li, Songming Tang, Keju Gu, Shengquan Chen   +4 more
wiley   +1 more source

Frequency of Basic English Grammatical Structures: A Corpus Analysis. [PDF]

J Mem Lang, 2007
Roland D, Dick F, Elman JL.
europepmc   +1 more source

Single‐Molecule Imaging of Endogenous RNA Using a Miniaturized and Circularly Permuted CRISPR‐Cas13 Degron‐Masking System CDegSR

Advanced Science, EarlyView.
CDegSR, a new tool for imaging RNA at single molecule level in living cells was developed by researchers. Background noise was eliminated by protein engineering and making it degrade when not bound to its target. This allowed individual RNA molecules to be clearly imaged and tracked.
Shipeng Shao, Hongchen Zhang
wiley   +1 more source

What Does <i>That</i> Mean? Complementizers and Epistemic Authority. [PDF]

Open Mind (Camb)
Tollan R, Palaz B.
europepmc   +1 more source

Functional Complementation and Genetic Deletion Studies of KirBac Channels [PDF]

Journal of Biological Chemistry, 2010
Jennifer J. Paynter, Isabelle Andres-Enguix, Philip W. Fowler, Stephen Tottey, Wayland Cheng, Decha Enkvetchakul, Vassiliy N. Bavro, Yoshio Kusakabe, Mark S.P. Sansom, Nigel J. Robinson, Colin G. Nichols, Stephen J. Tucker   +11 more
openaire   +1 more source

FOXP1 Knockdown Reprograms Th9 CAR‐T Cells to Overcome Antigen Escape

Advanced Science, EarlyView.
FOXP1 knockdown enhances Th9 CAR‐T cell function by promoting IL‐9 production, effector activation, and reduced exhaustion. Reprogrammed Th9 CAR‐T cells strengthen direct tumor killing and activate endogenous antitumor immunity through dendritic cells and CD8+ T cells, thereby suppressing both antigen‐positive and antigen‐loss tumor growth and ...
Yihan Zhu, Xingwei Xie, Xiaohuan Wu, Suidong Ouyang, Yang Zhou, Kang Wen, Yutong Zhong, Yuyang Chen, Handuo Wang, Yuan Gao, Ling Jiang, Hui Li, Wenli Zhao, Abai Xu, Enguang Bi   +14 more
wiley   +1 more source

The Acquisition of Directionals in Two Mayan Languages. [PDF]

Front Psychol, 2019
Pye C, Pfeiler B.
europepmc   +1 more source

Molecular Glue Degraders Enhance CAPRIN1‐Dependent Lysosomal Degradation of APP and Reduce Amyloid β in Alzheimer's Disease

Advanced Science, EarlyView.
A new class of lysosome‐directed molecular glue degraders selectively enhance CAPRIN1–APP interactions, driving APP degradation and reducing amyloid‐β production in human neurons and Alzheimer's disease mouse models. This CAPRIN1‐dependent targeted protein degradation strategy reveals a previously unrecognized therapeutic approach for disrupting the ...
Sunghan Jung, Xu Wang, Bin Liu, Raktim Roy, Nancy Jaiswal, Ratan K. Rai, Yuichiro Takagi, Cen Gao, Lifan Zeng, Ho‐Yin Lo, Reagan K. Wohlford, Ryan K. Higgins, Bruce T. Lamb, Anantha Shekhar, Anita C. Bellail, Chunhai Hao   +15 more
wiley   +1 more source

Free indirect discourse as logophoric context. [PDF]

Linguist Philos
Charnavel I.
europepmc   +1 more source