Results 21 to 30 of about 294,344 (225)
, 2022 Deletion event in the wing of Drosophila ...
MARCO ANTONIO CARBALLO ONTIVEROS (12407764)
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FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Deletion and Complementation Analysis of the Biotin Gene Cluster of Escherichia coli [PDF]
Journal of Bacteriology, 1972 Genetic deletions that terminate within the cluster of genes needed for biotin biosynthesis in Escherichia coli have been isolated and mapped by transduction with phages lambda and P1. These deletions order the point mutations in each of the five genes. Mutations causing biotin dependence were incorporated into λ
P P, Cleary, A, Campbell
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FEBS Letters, EarlyView.Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
Complementizer cliticization in Tagalog and English
, 1999 This paper investigates the conditions on the allomorphy of the Tagalog "linker". When the linker is used as a declarative complementizer, the affixal version has the same distribution as the null complementizer in English, while the free-standing linker
Richards, Norvin
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A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
DNA ligase LigE increases bacterial transformation with damaged extracellular DNA
FEBS Letters, EarlyView.The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan +4 more
wiley +1 more source
COLLOQUIUM-Complementizer agreement is clitic doubling: A uniform analysis of intervention effects
, 2021 Based on new data on intervention effects on complementizer agreement in West-Germanic varieties, I show that neither Agree nor PF analyses of complementizer agreement can account for the full range of data. Instead, I argue that complementizer agreement
A.H.J. van Alem
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The semi-complementizer shuō and non-referential CPs in Mandarin Chinese [PDF]
, 2021 The empirical focus of this paper is the syntactic status of the semi-complementizer shuō grammaticalized from verbs of saying, in Mandarin Chinese. Such elements have been shown to exhibit atypical patterns compared to that in English, which triggers ...
Huang, Jiahui, Jiahui Huang
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