Results 111 to 120 of about 10,963 (227)

Androgenetic alopecia: a review [PDF]

, 2017
Purpose Androgenetic alopecia, commonly known as male pattern baldness, is the most common type of progressive hair loss disorder in men. The aim of this paper is to review recent advances in understanding the pathophysiology and molecular mechanism
Caro, Gemma, Fortuna, MARIA CATERINA, Lenzi, Andrea, Lolli, Francesca, Lombardo, Francesco, Pallotti, Francesco, Rossi, Alfredo, Sansone, Andrea   +7 more
core   +1 more source

Complete Androgen Insensitivity Syndrome and Literature Review

Journal of Human Growth and Development, 2019
Backgroung: Complete Androgen Insensitivity Syndrome (CAIS) has been reported since 1923, but in 1953 it became known as “testicular feminization”. It is a rare recessive genetic disorder linked to the X chromosome that results in different mutations in the androgen receptor.
Mauricio Giusti Calderon, Carolina Maria Barbosa Lemos, Mariana Drigo Alem, Thais Cristina Pinelli, Rodrigo Daminello Raimundo   +4 more
openaire   +2 more sources

Outcomes of pregnancies that screened positive for sex chromosome aneuploidy ascertained via cell‐free DNA screening

Journal of Genetic Counseling, Volume 34, Issue 5, October 2025.
Abstract Cell‐free DNA screening (cfDNA), also referred to as noninvasive prenatal screening (NIPS), is utilized to screen for fetal chromosomal aneuploidies during pregnancy, including sex chromosome aneuploidies (SCAs). All patients within our center are offered diagnostic testing following a positive cfDNA for an SCA, but not all patients pursue ...
Cali FitzGerald, Shama P. Khan, Pranali Shingala, Gary Heiman, Elena Ashkinadze   +4 more
wiley   +1 more source

Complete Androgen Insensitivity Syndrome and bone mass. Basal evaluation and after long term estrogen treatment [PDF]

, 2015
L’osso è un tessuto target per estrogeni ed androgeni ma l’azione singola e la sinergia tra i due non sono compresi interamente. Le donne affette da Sindrome da Insensititvità Completa agli Androgeni (CAIS) hanno un cariotipo 46XY ma presentano una ...
Berra, Marta <1979>
core   +1 more source

G Protein‐Coupled Receptor Signaling: Implications and Therapeutic Development Advances in Cancers

MedComm, Volume 6, Issue 10, October 2025.
G protein‐coupled receptors (GPCRs) are the dynamic protein family in the human genome. GPCR dysregulation aids in the advancement of cancer through increased migration, survival, and proliferation. Novel treatments that target GPCR signaling include orthosteric ligands, biased receptor mutants, PROTACs, and antibody–drug conjugates.
Inamu Rashid Khan, Sana Khurshid, Saud Almawash, Rakesh Kumar, Ammira S. Al‐Shabeeb Akil, Ajaz A. Bhat, Muzafar A. Macha   +6 more
wiley   +1 more source

Society for Endocrinology Clinical Practice Guideline for the Evaluation of Androgen Excess in Women

Clinical Endocrinology, Volume 103, Issue 4, Page 540-566, October 2025.
ABSTRACT Context Androgen excess is common in women and refers to clinical or biochemical evidence of elevated androgenic steroids such as testosterone. It is associated with underlying polycystic ovary syndrome in the majority of cases. However severe androgen excess is less common and may indicate the presence of underlying adrenal or ovarian ...
Yasir S. Elhassan, James M. Hawley, Leanne Cussen, Ali Abbara, Sophie A. Clarke, Punith Kempegowda, Rima K. Dhillon‐Smith, Puja Thadani, Maureen Busby, Lucy Owusu‐Darkwah, Rachel Marrington, W. Colin Duncan, Robert K. Semple, Richard Quinton, Michael W. O'Reilly   +14 more
wiley   +1 more source

Hypospadias as a novel feature in spinal bulbar muscle atrophy [PDF]

, 2016
Spinal and bulbar muscle atrophy (SBMA) is an X-linked neuromuscular disorder caused by CAG repeat expansions in the androgen receptor (AR) gene.
Almqvist, C., Frisén, L., Nordenskjöld, A., Nordenström, A., Nordenvall, A.S., Paucar, M.   +5 more
core   +1 more source

Androgen receptor gene mutations in 46, XY females

Journal of Research in Medical Sciences, 2006
The androgen insensitivity syndrome is a heterogeneous disorder with a wide spectrum of phenotypic abnormalities, ranging from complete female to ambiguous forms that more closely resemble males.
Mir Davood Omrani, Soraya Saleh Gargari
doaj  

The role of hypothalamus-pituitary-adrenal (HPA)-like axis in inflammatory pilosebaceous disorders [PDF]

, 2020
Skin is the largest peripheral endocrine organ and functions as a hormone target and endocrine gland. A cutaneous hypothalamus-pituitary-adrenal (HPA)-like axis enables the skin to respond to stress and regulates its steroidogenic activity.
Clark, Ashley K, Saric-Bosanac, Suzana, Shi, Vivian Y, Sivamani, Raja K   +3 more
core  

A CASE REPORT OF COMPLETE ANDROGEN INSENSITIVITY SYNDROME RISING A CONCERN ABOUT THE TIME OF SURGERY AND THE ROLE OF PARENTS' BEHAVIOR

Journal of IMAB
Purpose: This case study refers to a case of complete androgen insensitivity syndrome, which presented with amenorrhea back in the past. Case: After conformation of the diagnosis, parents decided not to reveal the condition’s specifics to the patient. At
Viktoria Spasova, Liliya Koleva, Svetlana Shumarova, D. Hristova, V. Pencheva, Anatoli Kolev, Bozhidar Karamishev, Daria Koleva, Vladislav Petkov, Svetozar Marangozov, Vesela Karamisheva   +10 more
semanticscholar   +1 more source