Results 91 to 100 of about 834 (196)

Worsening Heart Failure From Decreased Atrioventricular Synchronization Rate of a Leadless Pacemaker

JACC: Case Reports
Background: Atrioventricular synchronous pacing with a leadless pacemaker is a therapy used in patients with atrioventricular block. However, atrial oversensing may cause an increase in heart rate, with resulting atrioventricular dyssynchrony.
Kazuku Ishihara, MD, Takenori Ikoma, MD, Makoto Sano, MD, Terumori Satoh, MD, Keisuke Iguchi, MD, Atsushi Sakamoto, MD, Kenichiro Suwa, MD, Yoshihisa Naruse, MD, Hayato Ohtani, MD, Yuichiro Maekawa, MD   +9 more
doaj   +1 more source

Glycosylation of the murine cardiac channel TRPM4 is altered by the pathogenic p.I376T variant

Experimental Physiology, EarlyView.
Abstract TRPM4 is a calcium‐activated, voltage‐modulated, non‐selective cation channel expressed in various tissues, including the heart. In 2016, we reported on a large French family with progressive heart block type I carrying the variant TRPM4 p.I376T.
Sabrina Guichard, Emanuele di Lorenzo, Dominic Schneiter, Maria Essers, Prakash Arullampalam, Jean‐Sébastien Rougier, Hugues Abriel   +6 more
wiley   +1 more source

Atrioventricular block as a common problem in elderly patients with coronary artery disease: clinical observation

Медицина неотложных состояний
Complete atrioventricular block is a dangerous complication in elderly patients with coronary artery disease that requires surgical treatment. Treatment of elderly patients with coronary artery disease and atrioventricular block is a debatable problem ...
O.O. Zhurba
doaj   +1 more source

Cardiac remodelling in type 2 diabetes: Pathophysiological mechanisms and opportunities for multiscale computational modelling and simulation

The Journal of Physiology, EarlyView.
Abstract figure legend Overview of multiscale cardiac remodelling in type 2 diabetes and how to model and simulate these changes using a human‐based, multiscale computational framework. Cardiac remodelling in type 2 diabetes occurs at ionic channel, protein, cellular, tissue and whole‐organ level, affecting the electrophysiological function, mechanical
Ambre Bertrand, Jakub Tomek, Blanca Rodriguez   +2 more
wiley   +1 more source

A 13 Year-old Girl with Complete AVSD (Intermediate subtype) and Total AV Block

Qanun Medika: Jurnal Kedokteran Fakultas Kedokteran Universitas Muhammadiyah Surabaya
Atrioventricular septal defects (AVSD) constitute a spectrum of anomalies caused by abnormal endocardial cushion defects. Many classifications have been used to describe AVSD. There is generally subclassified into complete and partial forms.
I Ketut Alit Utamayasa, Prima Hari Nastiti, Taufiq Hidayat, Mahrus Abdur Rahman   +3 more
doaj   +1 more source

Mathematical model of the zebrafish ventricular cardiomyocyte action potential and calcium transient

The Journal of Physiology, EarlyView.
Abstract figure legend This study presents the development and validation of the first biophysically detailed computational model of the zebrafish ventricular action potential (AP). The model is based on a human cardiomyocyte framework and reparameterized using published and newly generated patch‐clamp recordings of zebrafish ionic currents.
Ludovica Cestariolo, Zachary D. Long, Arie O. Verkerk, Jose M. Ferrero, T. Alexander Quinn, Jose F. Rodriguez Matas   +5 more
wiley   +1 more source

Incidence of atrioventricular conduction disturbances and need for pacemaker implantation in patients after endovascular aortic valve replacement

Сибирский научный медицинский журнал
The aim of the study was to evaluate predictors of cardiac conduction disturbance associated with increased risk of temporary and permanent pacemaker implantation after endovascular aortic valve replacement (TAVR). Material and methods.
Yu. Yu. Stolbikov, G. V. Matyushin, A. V. Protopopov, E. V. Samokhvalov, O. P. Ishchenko, V. O. Kobanenko   +5 more
doaj   +1 more source

Repolarization adaptation to rapid change in heart rate in human models – a review

The Journal of Physiology, EarlyView.
Abstract figure legend This review focuses on non‐invasive assessment of repolarization duration and dispersion (heterogeneity) adaptation to change in heart rate (HR). HR was increased incrementally by left atrial pacing during an electrophysiology (EP) study and by a bolus injection of atropine and in a step up/down fashion by repeated right atrial ...
Lennart Bergfeldt, Karl‐Jonas Axelsson, Pia Dahlberg, Farzad Vahedi, Gunilla Lundahl, Lennart Gransberg   +5 more
wiley   +1 more source

Unveiling sex dimorphism in the healthy cardiac anatomy: Fundamental differences between male and female heart shapes

The Journal of Physiology, EarlyView.
Abstract figure legend We present a shape modelling‐based morphological analysis of sex differences in cardiac anatomy. We conduct our analysis on 456 healthy subjects from the UK Biobank (227M/229F) to uncover sex‐based differences in healthy cardiac morphology.
Beatrice Moscoloni, Cameron Beeche, Julio A. Chirinos, Patrick Segers, Mathias Peirlinck   +4 more
wiley   +1 more source

Potential health benefits of cold‐water immersion: the central role of PGC‐1α

The Journal of Physiology, EarlyView.
Abstract figure legend Cold‐water immersion (CWI) elicits autonomic, somato‐motoric (shivering thermogenesis), endocrine and metabolic, sensory transduction, and local biophysical effects that may converge on the transcriptional co‐activator PGC‐1α (centre).
Erich Hohenauer, Wafa Douzi, Johannes Burtscher   +2 more
wiley   +1 more source