Results 141 to 150 of about 3,369,792 (260)
Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank
FEBS Open Bio, EarlyView.Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer +7 more
wiley +1 more source
Open MathematicsLet SS be a semigroup. In this study, we first introduce the Green’s digraphs and Green’s graphs related to the Green’s relations L{\mathscr{L}}, R{\mathscr{R}}, and J{\mathscr{J}} of SS.
Cheng Yanliang, Shao Yong, Ma Xuanlong
doaj +1 more source
Leaps: an approach to the block structure of a graph [PDF]
To study the block structure of a connected graph G=(V,E), we introduce two algebraic approaches that reflect this structure: a binary operation + called a leap operation and a ternary relation L called a leap system, both on a finite, nonempty set V ...
Mulder, H.M., Nebesky, L.
core
Cover Pebbling Thresholds for the Complete Graph
, 2005 We obtain first-order cover pebbling thresholds of the complete graph for Maxwell Boltzmann and Bose Einstein ...
Yerger, Carl R. +2 more
core +1 more source
FEBS Open Bio, EarlyView.Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata +3 more
wiley +1 more source
Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells
FEBS Open Bio, EarlyView.Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla +10 more
wiley +1 more source
Bounds on the Threshold Ramsey Multiplicity of Ramsey Numbers with Many Colors
MathematicsThe Ramsey number R(s,t) is the least integer n such that any coloring of the edges of Kn with two colors produces either a monochromatic Ks in one color or a monochromatic Kt in the other. If s=t, we call R(s,s) a diagonal Ramsey number.
Bryce Alan Christopherson +1 more
doaj +1 more source
FEBS Open Bio, EarlyView.During the current opioid crisis, the majority of overdose deaths are attributed to ultra‐potent synthetic opioids, such as fentanyl. While fentanyl exerts its action via opioid receptors, we propose that potassium channels in the brain blood vessels may also sense fentanyl.
Shiwani Thapa +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao +23 more
wiley +1 more source