Results 31 to 40 of about 3,118,294 (254)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
The Ceresa class and tropical curves of hyperelliptic type
Forum of Mathematics, SigmaWe define a new algebraic invariant of a graph G called the Ceresa–Zharkov class and show that it is trivial if and only if G is of hyperelliptic type, equivalently, G does not have as a minor the complete graph on four vertices or the loop of three ...
Daniel Corey, Wanlin Li
doaj +1 more source
Heuristic algorithms for best match graph editing
Algorithms for Molecular Biology, 2021 Background Best match graphs (BMGs) are a class of colored digraphs that naturally appear in mathematical phylogenetics as a representation of the pairwise most closely related genes among multiple species.
David Schaller +3 more
doaj +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
A graph rewriting programming language for graph drawing [PDF]
, 1998 This paper describes Grrr, a prototype visual graph drawing tool. Previously there were no visual languages for programming graph drawing algorithms despite the inherently visual nature of the process.
Rodgers, Peter
core +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
The t-Pebbling Number of Jahangir Graph [PDF]
, 2012 Given a configuration of pebbles on the vertices of a connected graph G, a pebbling move (or pebbling step) is defined as the removal of two pebbles from a vertex and placing one pebble on an adjacent vertex.
Samuel Jeyaseelan, S. +2 more
core +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Convolution operators and the discrete Laplacian [PDF]
, 2009 PhDIn this thesis, we obtain new results for convolution operators on homogeneous spaces and give applications to the Laplacian on a homogeneous graph. Some of these results have been published in joint papers [13, 14] with my supervisor.
Chen, Chung-Chuan
core +4 more sources
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source