Results 71 to 80 of about 292,611 (264)
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
The edge-regular complete maps
Open Mathematics, 2020 A map is called edge-regular if it is edge-transitive but not arc-transitive. In this paper, we show that a complete graph Kn{K}_{n} has an orientable edge-regular embedding if and only if n=pd>3n={p}^{d}\gt 3 with p an odd prime such that pd≡3{p}^{d ...
Yu Xue, Lou Ben Gong
doaj +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Discrete Applied Mathematics, 1990 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Hammer, Peter L., Maffray, Frédéric
openaire +2 more sources
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Isolated Single Valued Neutrosophic Graphs [PDF]
Neutrosophic Sets and Systems, 2016 Many results have been obtained on isolated graphs and complete graphs. In this paper, a necessary and sufficient condition will be proved for a single valued neutrosophic graph to be an isolated single valued neutrosophic graph.
Said Broumi +3 more
doaj
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Linear Algebra and its Applications, 2016 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Shaked-Monderer, Naomi +3 more
openaire +3 more sources
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Converting Tessellations into Graphs: From Voronoi Tessellations to Complete Graphs
MathematicsA mathematical procedure enabling the transformation of an arbitrary tessellation of a surface into a bi-colored, complete graph is introduced. Polygons constituting the tessellation are represented by vertices of the graphs.
Artem Gilevich +4 more
doaj +1 more source