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Twin pregnancy with complete hydatidiform mole
Arkhiv patologii, 2017The paper describes a case of twin pregnancy with complete hydatidiform mole (CHM). According to the data available in the literature, the concurrence of CHM with a normal placenta and a viable fetus occurs in 1 per 20,000-100,000 pregnancies, requires a differential diagnosis with partial hydatidiform mole and placental mesenchymal dysplasia, and is ...
I N, Voloshchuk +3 more
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Mechanism of Origin of Complete Hydatidiform Moles
Obstetrical & Gynecological Survey, 1980Complete or 'true' hydatidiform mole, an abnormality of human gestation, is characterized by hydropic degeneraton of all placental villi, marked hypertrophy of the trophoblast, absence of a fetus and a propensity to become malignant. The chromosome constitution of complete moles is usually 46,XX, and Kajii et al.
P A, Jacobs +4 more
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“Bunch of grapes” in complete hydatidiform mole
Abdominal Radiology, 2016Complete hydatidiform mole is a common cause of gestational bleeding of the first trimester, commonly assessed by ultrasound. It represents an abnormal proliferation of trophoblastic tissue, with no fetal formation, just hydropic villi. These abnormal villi seen in ultrasound are compared to a "bunch of grapes," a classic description of this disease.
Eduardo Kaiser Ururahy Nunes Fonseca +3 more
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Complete hydatidiform mole in higher-order multiple pregnancies
Minerva Obstetrics and Gynecology, 2022Molar degeneration of the trophoblast is a rare, yet possible, complication of pregnancies. Complete hydatidiform mole is the most common histological type among all trophoblastic tumors and it is the result of the fertilization of an empty oocyte from two sperms or by one sperm that then duplicates.
Sileo F. G. +5 more
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Cytogenetics of trophoblasts from complete hydatidiform moles
Cancer Genetics and Cytogenetics, 1987The risk of developing choriocarcinoma following a complete hydatidiform mole (CHM) is 2000-4000 times greater than the risk following a normal pregnancy. To understand more fully the increased susceptibility of the molar trophoblast to malignant transformation, we separated the trophoblastic cells from the stromal cells in 14 complete moles and ...
R, Habibian, U, Surti
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Overexpression of GRP78 in complete hydatidiform moles
Gynecologic Oncology, 2012Hydatidiform moles, subdivided into partial moles (PM) and complete moles (CM), are abnormal pregnancies with a disturbed invasive behavior. We had previously shown that MMP-2 and p53 proteins are overexpressed in CM versus PM, and that in primary cytotrophoblasts p53 protein is stabilized by complexing to the 78kDa glucose-regulated protein (GRP78 ...
Ribaux, P +7 more
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Rare case of peritoneal complete hydatidiform mole
Journal of Obstetrics and Gynaecology Research, 2014AbstractA 23‐year‐old woman, gravida 1, para 1, was transferred to our hospital with acute lower abdominal pain and vital signs consistent with shock. Her urine concentration of human chorionic gonadotrophin was 8000 mIU/mL. Transvaginal ultrasound revealed an echo‐free space with mosaic echo pattern in the right adnexal area and no gestational sac in ...
Hajime, Ota +4 more
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Postmenopausal complete hydatidiform mole: A case report
Maturitas, 2008Gestational trophoblastic neoplasia (GTN) is a disease with a course of trophoblastic proliferation, and histologically classified as partial hydatidiform mole, complete mole, invasive and metastatic mole, choriocarcinoma and placental site trophoblastic tumor.
BAŞPINAR, Şirin +5 more
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Complete hydatidiform mole with a coexistent embryo
Human Pathology, 1996We describe a case of a complete hydatidiform mole with a coexistent embryo. A 19-year-old Hispanic woman presented with an intrauterine pregnancy at 7 weeks gestational age. An ultrasound evaluation at that time showed a gestational sac and fetal heart activity was observed.
R N, Baergen +4 more
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