Results 91 to 100 of about 31,122 (308)

Vestibular Patient Journey: Insights From Vestibular Disorders Association (VeDA) Registry

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Vestibular symptoms impose a high burden of disability. Understanding real‐world diagnostic and treatment pathways can identify care gaps and guide interventions. We aimed to characterize symptom profiles, diagnostic trends, provider involvement, and treatment patterns in vestibular disorders.
Ali Rafati, Sami I. Nassar, Shaun A. Nguyen, Patricia L. Gerend, Michael C. Schubert, Michael T. Teixido, Frederick A. Godley, Joel A. Goebel, Cynthia A. Ryan, Habib G. Rizk, Amir Kheradmand   +10 more
wiley   +1 more source

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz, Christopher H. Thompson, Linda C. Laux, Alfred L. George Jr.   +3 more
wiley   +1 more source

Open intersection numbers and free fields

Nuclear Physics B, 2017
A complete set of the Virasoro and W-constraints for the Kontsevich–Penner model, which conjecturally describes intersections on moduli spaces of open curves, was derived in our previous work. Here we show that these constraints can be described in terms
Alexander Alexandrov
doaj   +1 more source

Coniveau $2$ complete intersections and effective cones [PDF]

, 2008
The goal of this paper is first of all to propose a strategy to attack the generalized Hodge conjecture for coniveau $2$ complete intersections, and secondly to state a conjecture concerning the cones of effective cycle classes in intermediate dimensions.
Voisin, Claire
core   +1 more source

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

Annals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao, Qiu‐Ping Zhao, Run‐Yun Li, Wei Chen, Huan‐Huan Song, Wan‐Jin Chen, Ying Fu   +6 more
wiley   +1 more source

Neurovascular Contacts in the Pathophysiology of Neuralgic Amyotrophy: An Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuralgic amyotrophy (NA) is a prevalent, monophasic, multifocal immune‐mediated neuropathy. A distinctive characteristic of the disease is the occurrence of nerve or fascicle constrictions and torsions (NA‐associated focal nerve lesions, NAFL). The pathophysiology underlying this phenomenon remains to be fully elucidated.
Johannes Fabian Holle, Andreas Leha, Volker Limmroth, Wolfram Windisch, Maximilian Zimmermann   +4 more
wiley   +1 more source

Predicting urban signal-controlled intersection congestion events using spatio-temporal neural point process

International Journal of Digital Earth
The urban traffic signal-controlled intersections are of great significance for solving the problem of urban road congestion. Previous research on congestion prediction mainly aggregated data at the level of road segments or traffic flow at a coarse ...
Jianlong Wang, Xiaoqi Duan, Peixiao Wang, A.-Gen Qiu, Zeqiang Chen   +4 more
doaj   +1 more source

The intersection of the spectra of operator completions

Linear Algebra and its Applications, 2003
Let \(A\), \(B\), \(C\) given operators in certain spaces. The operator matrix \(Q= \left(\begin{smallmatrix} A & C\\ ? & B\end{smallmatrix}\right)\) is to be completed by an operator \(X\) into \(M_X= \left(\begin{smallmatrix} A & C\\ X & B\end{smallmatrix}\right)\). In the present paper, the intersection of the spectra of \(M_X\) is considered when \(
Ren, Fang-Guo, Du, Hong-Ke, Cao, Huai-xin   +2 more
openaire   +2 more sources

Gale duality for complete intersections [PDF]

, 2008
International audienceWe show that every complete intersection defined by Laurent polynomials in an algebraic torus is isomorphic to a complete intersection defined by master functions in the complement of a hyperplane arrangement, and vice versa.
Sottile, Frank, Frank Sottile, Bihan, Frédéric, Bihan, Fr��d��ric, Frédéric Bihan   +4 more
core   +1 more source

A 17 Year Old With Developmental Delay Presenting With Increasing Confusion and Imbalance

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Methylmalonic acidemia is an autosomal recessive genetic disorder primarily caused by defects in methylmalonyl‐CoA mutase and cobalamin (vitamin B12) metabolism. These defects disrupt the tricarboxylic acid cycle and oxidative phosphorylation, leading to the abnormal accumulation of metabolic products such as methylmalonic acid, propionic acid,
Wei Zhao, Yingli Zhang, Hongliang Zheng
wiley   +1 more source