Results 61 to 70 of about 603,535 (296)

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács   +8 more
wiley   +1 more source

Use of cryogenic buoyancy systems for controlled removal of heavy objects from the seabed

open access: yes, 2009
The concept design of a lightweight cryogenic marine heavy lift buoyancy system has been investigated. The approach makes use of a novel cryogenic system for provision of buoyancy within the ocean environment. The objective is to be able to lift or lower
Boyd, S.W.   +2 more
core   +1 more source

Another proof of Banaschewski's surjection theorem [PDF]

open access: yesCategories and General Algebraic Structures with Applications, 2019
We present a new proof of Banaschewski's theorem stating that the completion lift of a uniform surjection is a surjection. The new procedure allows to extend the fact (and, similarly, the related theorem on closed uniform sublocales of complete uniform ...
Dharmanand Baboolal   +2 more
doaj   +1 more source

Comparison of path-complete Lyapunov functions via template-dependent lifts

open access: yesNonlinear Analysis: Hybrid Systems, 2022
This paper investigates, in the context of discrete-time switching systems, the problem of comparison for path-complete stability certificates. We introduce and study abstract operations on path-complete graphs, called lifts, which allow us to recover previous results in a general framework.
Debauche V.   +2 more
openaire   +3 more sources

Adherence to Protocol Recommendations for Children With Wilms Tumour in Two Consecutive Studies in the United Kingdom and Ireland—Does Variation Matter?

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait   +23 more
wiley   +1 more source

Applicability evaluation of plunger lift technology in shale gas wells

open access: yesFrontiers in Energy Research
The accumulation of liquid in gas wells is a common problem in the later stages of shale gas production. The plunger lift is currently one of the most economically effective methods for removing accumulated liquid in gas wells, but its applicability is ...
Yu Fan   +5 more
doaj   +1 more source

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson   +3 more
wiley   +1 more source

Asymptotic lifting for completely positive maps

open access: yesJournal of Functional Analysis
v2: 25 ...
Forough, Marzieh   +2 more
openaire   +4 more sources

Liftings of functions with values in a completely regular space [PDF]

open access: yesProceedings of the American Mathematical Society, 1980
Let T be a completely regular space, let ( Ω , F , μ ) (\Omega ,\mathcal {F},\mu ) be complete probability space, and let ρ : L ∞ ( μ ) →
Edgar, G. A., Talagrand, Michel
openaire   +2 more sources

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski   +9 more
wiley   +1 more source

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