Results 81 to 90 of about 2,518,594 (294)
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Integrated Gas Lift Completion String for Ultra-deep Reservoir
The Kennyark Oilfield in Kazakhstan belongs to a low-porosity, ultralow-permeability and ultra-deep oil reservoir, which faces with many technical problems when produced by conventional gas lift string.
Zhang Peng
doaj
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Dynamic Stability and Control Authority Blending in Lift-Plus-Cruise eVTOL Transition Flight
Lift-plus-cruise electric vertical takeoff and landing (eVTOL) aircraft exhibit complex stability characteristics during transition flight, when rotor-borne and wing-borne regimes coexist.
João Pedro Spadão +3 more
doaj +1 more source
The Lifting Problem is NP Complete
Let $M$ be a 3-manifold. Every knotted (embedded) surface in $M \times \R$ can be moved via an ambient isotopy in such a way that its projection into $M$ is a generic surface. A surface is generic if every point on it is either a regular, double or triple value - the transversal intersection of 1, 2 or 3 embedded surface sheets, or a "branch value ...
openaire +2 more sources
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Parametric analysis of wing planforms to determine an optimal wing design
In designing of Unmanned Aerial Vehicle (UAV), selection of an optimal wing design is a crucial part of complete UAV design process. This research explores the different aerodynamic parameters and the comparison of different wing planforms to ascertain ...
Manish Kumar Chauhan +2 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
The Lift Project: Blue and Green Should Often be Seen
The Lift Project is an evidence-based mental health and wellbeing program that draws together the findings of over 400 studies from the disciplines of Neuroscience, Lifestyle Medicine and Positive Psychology.
Morton, Darren
core +1 more source

