Results 91 to 100 of about 49,191 (262)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Investigation of the Influence of Different Flapping Wing Motion Characteristics on Aerodynamic Parameters under Incoming Flow [PDF]

Journal of Applied Fluid Mechanics
There is high flight efficiency of flapping wing aircraft, and its hovering ability, wind loading rating, maneuverability and concealment are better than that of multi-rotor and fixed-wing aircraft. In this paper, the bionic flapping wing is taken as the
Z. Guo, R. Liu, S. Zheng, J. Xu, J. Chang   +4 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Simulation Modeling of Truck Load of Skidding Tractors with a Grapple for Chokerless Skidding

Croatian Journal of Forest Engineering, 2019
The objective of the present study is to define mass distribution laws for a bundle of trees using the methods of statistical simulation modeling in order to calculate chokerless skidding tractors lift capacity.
Ilya R. Shegelman, Pavel V. Budnik, Vyacheslav N. Baklagin   +2 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Deformations of Theta Integrals and A Conjecture of Gross-Zagier

Forum of Mathematics, Sigma
In this paper, we complete the proof of the conjecture of Gross and Zagier concerning algebraicity of higher Green functions at a single CM point on the product of modular curves. The new ingredient is an analogue of the incoherent Eisenstein series over
Jan H. Bruinier, Yingkun Li, Tonghai Yang   +2 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Comparing closure compliance and ease of use for consumer product packs designed to reduce access to children.

PLoS ONE
Child impeding packs are difficult for children to open so protect them from unintended access to hazardous contents inside the pack. However, if packs are difficult for adults to open, in normal usage scenarios, this may result in a higher occurrence of
Annalise Richmond, David C Schwebel, Clara Ng Pak Leung, Elke Vallez, Heidi Lesage, Raf Degeyter, Zhiwu Liang, Gerard Stijntjes   +7 more
doaj   +1 more source

Higher-order Delsarte Dual LPs: Lifting, Constructions and Completeness

CoRR
50 ...
Coregliano, Leonardo Nagami, Jeronimo, Fernando Granha, Jones, Chris, Linial, Nati, Loyfer, Elyassaf   +4 more
openaire   +3 more sources

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source