Results 101 to 110 of about 2,518,594 (294)

Lifting Dual Connections with the Riemann Extension

Mathematics, 2020
Let (M,g) be a Riemannian manifold equipped with a pair of dual connections (∇,∇*). Such a structure is known as a statistical manifold since it was defined in the context of information geometry.
Stéphane Puechmorel
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Completions of matrices and the commutant lifting theorem

Journal of Functional Analysis, 1992
Some completion results for partially defined matrices with an infinite number of entries are obtained. These are then applied to obtain a description for the dilations of intertwining operators. In this context, a new proof of the commutant lifting theorem of Sz. Nagy and Foiaş [see \textit{C. Foiaş} and \textit{A. E.
openaire   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Lift

, 2000
Lift mechanism. Woman waiting nervously for lift. Passengers pushing their destination buttons; getting out, getting in. Woman gets out. Two remaining passengers – bike messenger and young woman – embracing.

core   +4 more sources

The closed-loop kinematics modeling and numerical calculation of the parallel hexapod robot in space

Advances in Mechanical Engineering, 2017
The Lie group Denavit–Hartenberg method and application in the parallel hexapod robot are researched. The hexapod robot and the ground form opened and closed loop alternately; the complete kinematics equation cannot be derived by Denavit–Hartenberg ...
Long Bai, Zhi-Feng Dong, Xin-Sheng Ge
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Champagne Cap Technique: a minimally invasive crestal sinus lift for severely atrophic maxilla

Annali di Stomatologia
Background: Implant rehabilitation in the posterior maxilla with severe atrophy remains a clinical and surgical challenge. Although widely used, the lateral window sinus lift is linked to longer healing times, increased invasiveness, and higher morbidity.
Federico Valenti Obino, Luca Testarelli, Dario Di Nardo, Luca Signorini, Massimo Galli   +4 more
doaj   +1 more source

Lift, Splat, Map: Lifting Foundation Masks for Label-Free Semantic Scene Completion

CoRR
Autonomous mobile robots deployed in urban environments must be context-aware, i.e., able to distinguish between different semantic entities, and robust to occlusions. Current approaches like semantic scene completion (SSC) require pre-enumerating the set of classes and costly human annotations, while representation learning methods relax these ...
Arthur Zhang, Rainier Heijne, Joydeep Biswas   +2 more
openaire   +3 more sources