Results 91 to 100 of about 102,220 (261)

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Metric dimension of complete metric spaces [PDF]

Proceedings of the American Mathematical Society, 1970
openaire   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Fixed points of contractive dominated mappings on a closed ball in an ordered quasi partial metric space

Le Matematiche, 2015
In this paper, we obtain some fixed point theorems for dominated mappings satisfying locally contractive conditions on a closed ball in a left K-sequentially O-complete ordered quasi-partial metric space and in a right K-sequentially O-complete ordered ...
M. Arshad, A. Shoaib, Ismat Beg
doaj  

How phagocytic cells kill bacteria: Lessons from a professional killer

FEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source

A unique common coupled fixed point theorem for four maps under Ψ-Φ contractive condition in partial metric spaces

Cubo, 2012
In this paper, we obtain a unique coupled common fixed point theorem for four maps in partial metric spaces.En este artículo obtenemos un teorema del punto fijo clásico acoplado único para cuatro aplicaciones en espacios métricos parciales.
K.P.R Rao, G.N.V Kishore, Nguyen Van Luong   +2 more
doaj  

Fixed points of two interpolative cyclic contractions in b-metric spaces

Heliyon
The b-metric space happens to be one of the of most significant and non-trivial generalizations of metric spaces. In this paper, we introduce the concepts of Kannan type and Ćirić-Reich-Rus type cyclic contractions in b-metric spaces via interpolation ...
Darsana Devi, Pradip Debnath
doaj   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Some Results on Related Fixed Point Theorems in Two $S$-Metric Spaces

Journal of New Theory
In this study, by considering the technique in the theorem of Bollenbacher and Hicks, we obtain some related fixed point theorems involving two mappings on two related complete $S$-metric spaces with certain conditions.
Hakan Karayılan
doaj   +1 more source