Results 51 to 60 of about 828,524 (283)

New dynamic fixed point results in Menger spaces [PDF]

Surveys in Mathematics and its Applications, 2023
The objective of this paper is to generalize and improve some results in fixed point theorems in both complete metric space and Menger space. These results are generalizations of the analogous ones recently proved by Khojasteh [5], Demma [1], Yildirim ...
Besma Laouadi, Taki Eddine Oussaeif, Leila Benaoua, Liliana Guran, Ioana Camelia Tişe   +4 more
doaj  

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Completeness of the set of sub-σ-algebras

International Journal of Mathematics and Mathematical Sciences, 1993
A new metric is introduced on the set of all sub-σ-algebras of a complete probability space from functional analysis point of view. In this note, we will show that the resulting metric space is complete.
Xikui Wang
doaj   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

On the metrizability of suprametric space

Analele Stiintifice ale Universitatii Ovidius Constanta: Seria Matematica
The question of metrizability of suprametric space is answered positively. The observed metric coincides with a suprametric in a way that convergence and continuity are preserved between suprametric space and associated metric space along with the ...
Karapınar Erdal, Cvetković Marija
doaj   +1 more source

Some Extensions of Fixed Point Results over Quasi-JS-Spaces

Journal of Function Spaces, 2016
We introduce the notion of quasi-JS-metric space. After defining the basic topological properties of quasi-JS-metric space, we investigate fixed point of certain mapping in the frame of complete quasi-JS-metric space.
Maha Noorwali, Hamed H. Alsulami, Erdal Karapınar   +2 more
doaj   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Bounded time computation on metric spaces and Banach spaces

, 2017
We extend the framework by Kawamura and Cook for investigating computational complexity for operators occurring in analysis. This model is based on second-order complexity theory for functions on the Baire space, which is lifted to metric spaces by means
Schröder, Matthias, Steinberg, Florian
core   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Solution of the vacuum Kerr-Schild problem

, 2002
The complete solution of the vacuum Kerr-Schild equations in general relativity is presented, including the space-times with a curved background metric.
Boyer, Debever, Debney, Dozmorov, Gürses, Kerr, Kramer, Kóta, LászlóÁ Gergely, McIntosh, Nahmad-Achar, Newman, Thompson, Zoltán Perjés   +13 more
core   +1 more source