The complete mitochondrial genome of Holothuria atra (Holothuriida: Holothuriidae: Holothuria) and its structural characteristics. [PDF]
Wang J +9 more
europepmc +1 more source
ABSTRACT Intestinal ischemia/reperfusion (I/R) injury presents a biphasic pathology: an acute oxidative‐inflammatory phase leading to organ failure, and a recovery phase marked by mucosal dysfunction and bacterial translocation. The developed MPB@TA‐Cu‐Ma nanocomposite functions as a dual‐phase therapeutic platform with significant efficacy. It rapidly
Chenghao Qiu +15 more
wiley +1 more source
Complete mitochondrial genome of <i>Oxyartes lamellatus</i> (Phasmida: Lonchodidae: Necrosciinae). [PDF]
Li S, Qin Y, Luo T, Bian X.
europepmc +1 more source
Restoring Iron Homeostasis via Smoothened Inhibition: A Novel Strategy Against Hearing Loss
. ABSTRACT Sensorineural hearing loss (SNHL) induced by noise or aminoglycoside antibiotics is a significant public health concern without any FDA‐approved pharmaceutical therapies. Dysregulation of iron homeostasis and its subsequently induced ferroptosis has increasingly been identified as a key mechanism underlying cochlear hair cell (HC) damage ...
Huanyu Mao +9 more
wiley +1 more source
Complete Mitochondrial Genome of <i>Gyrodactylus nigeri</i> (Platyhelminthes: Monogenea). [PDF]
Yang Y +6 more
europepmc +1 more source
SpatialESD: Spatial Ensemble Domain Detection in Spatial Transcriptomics
ABSTRACT Spatial transcriptomics (ST) measures gene expression while preserving spatial context within tissues. One of the key tasks in ST analysis is spatial domain detection, which remains challenging due to the complex structure of ST data and the varying performance of individual clustering methods. To address this, we propose SpatialESD, a Spatial
Hongyan Cao +11 more
wiley +1 more source
We developed the enzyme‐responsive peptide SAp‐CD28 to selectively target CD28‐overexpressing T‐ALL cells. Following phosphatase‐mediated activation, SAp‐CD28 undergoes conformational switching and nanooligomerization, resulting in the disruption of CD28 downstream signaling.
Jun Li +10 more
wiley +1 more source
The complete mitochondrial genome sequence of <i>Kolla paulula</i> from Taiwan. [PDF]
Shih H-T +4 more
europepmc +1 more source
Plant Genetic Engineering: Technological Pathways, Application Scenarios, and Future Directions
This review maps the fast‐evolving landscape of plant genetic engineering, linking enabling platforms with trait‐focused applications in architecture optimization, stress resilience, yield improvement, and quality enhancement. It highlights how genome editing, transgenic strategies, and emerging multi‐gene approaches reshape breeding pipelines, while ...
Peilin Wang +4 more
wiley +1 more source
The complete mitochondrial genome analysis of <i>Elachiptera decipiens</i> (Loew, 1863) (Diptera: Chloropidae). [PDF]
Gu YY +5 more
europepmc +1 more source

