Results 271 to 280 of about 447,624 (394)

Targeting Itga8 Mitigates Neurogenic Bladder Fibrosis Driven by Trem2⁺ Macrophage‐Derived Fn1 via FAK/RhoA/ROCK Signaling

Advanced Science, EarlyView.
Normal bladders exhibit quiescent fibroblasts/macrophages, whereas neurogenic bladders show acute‐phase Itga8⁺ fibroblast expansion driven by Trem2⁺ macrophage‐secreted Fn1, which activates FAK/RhoA/ROCK signaling, promotes cytoskeletal remodeling, and upregulates pro‐fibrotic genes.
Jiaxin Wang, Siyuan Wang, Lida Ren, Xinqi Liu, Lei Zhang, Peng Hu, Wenchao Xu, Shuaixiang Zheng, Jihong Liu, Qing Ling   +9 more
wiley   +1 more source

Complete Mitochondrial Genome and Phylogenetic Analysis of <i>Turdus pallidus</i> (Passeriformes, Turdidae). [PDF]

Genes (Basel)
Zhan Q, Tang Y, Zhao X, Xue X, Chen Y, Huang Y.   +5 more
europepmc   +1 more source

Complete mitochondrial genome and phylogenetic implications of Chaunocephalus ferox (Digenea: Echinostomatidae), a critical pathogen for Oriental Stork conservation

Mengchao Zhou, Hongrui Liang, Z. Lv, Xiaotian Zhang, Yang Liu, Yaxian Lu, Hongyan Yu, Tian Hang, Lei Han, Yu Xu, Zhijun Hou   +10 more
openalex   +1 more source

The Complete Mitochondrial Genome and Novel Gene Arrangement of the Unique-Headed Bug Stenopirates sp. (Hemiptera: Enicocephalidae)

, 2012
Hu Li, Hui Liu, Aimin Shi, Pavel Štys, Xuguo Zhou, Wanzhi Cai   +5 more
openalex   +2 more sources

Complete mitochondrial genome of the mangrove killifish Kryptolebias hermaphroditus (Cyprinodontiformes, Rivulidae) [PDF]

, 2016
Hui-Su Kim, Dae‐Sik Hwang, Atsushi Hagiwara, Yoshitaka Sakakura, Jae‐Seong Lee   +4 more
openalex   +1 more source

Temporal Transcriptional Regulation of Human Neuronal Differentiation via Forward Programming

Advanced Science, EarlyView.
Single‐cell profiling of TF‐induced forward programming versus stepwise dual‐SMAD differentiation reveals that divergent trajectories set the pace of neurogenesis. OLIG TFs advance cell‐cycle exit via NOTCH modulation, while NEUROD2 later accelerates maturation. The study elucidates transcriptional mechanisms governing differentiation timing, providing
Lingling Zhu, Weiguang Wang, Jian Zhang, Lei Liu, Minpeng Huang, Lei Diao, Shuang Feng, Qiong Yang, Hao Qiu, Bing Pan, Renee A Reijo Pera, Ji Liu, Ninuo Xia, Fang Fang   +13 more
wiley   +1 more source

Genome characterization and phylogenetic analysis of the complete mitochondrial genome of <i>Eonemachilus caohaiensis</i> (Cypriniformes: Nemacheilidae). [PDF]

Mitochondrial DNA B Resour
Zeng S, Wang X, Lv Z, Wang W, Hu J, Zhang X.   +5 more
europepmc   +1 more source

Lactylation Enhances the Activity of Lactate Dehydrogenase A and Promotes the Chemoresistance to Cisplatin Through Facilitating DNA Nonhomologous End Junction in Lung Adenocarcinoma

Advanced Science, EarlyView.
Lactylation, linked to glycolysis, is poorly understood in regulation. It is found that LDHA is lactylated at Lys81/Lys318 by AARS1, boosting its activity and cellular lactylation via positive feedback in LUAD. Lactylation regulates NHEJ‐related proteins; their delactylation impairs NHEJ and increases cisplatin sensitivity, offering anticancer insights.
Jizhuo Li, Wenze Xun, Xijie Wang, Ruiguang Luo, Qifan Hu, Zhaocai Zhou, Jian Yuan, Yanan Wang, Xiaorui Wan, Tao Zhao, Tianyu Han, Jian‐Bin Wang   +11 more
wiley   +1 more source

The Complete Mitochondrial Genome of Deep-Sea Snipe Eel <i>Nemichthys curvirostris</i> (Anguilliformes: Nemichthyidae). [PDF]

Genes (Basel)
Jin X, Ma Y, Li L, Yuan Z, Ma C, Zhang F, Chen W, Zheng H, Li C, Zhu Z, Zhao M.   +10 more
europepmc   +1 more source

The complete mitochondrial genome of Lacerta bilineata and comparison with its closely related congener L. Viridis

, 2015
Sree Rohit Raj Kolora, Rui Faria, Anne Weigert, Stefan Schaffer, Annegret Grimm‐Seyfarth, Klaus Henle, Abdullah H. Sahyoun, Peter F. Stadler, Katja Nowick, Christoph Bleidorn, Martin Schlegel   +10 more
openalex   +2 more sources