Results 291 to 300 of about 270,006 (355)

Characterization of the Complete Mitochondrial Genome of <i>Angulyagra polyzonata</i> and Its Phylogenetic Status in Viviparidae. [PDF]

Animals (Basel)
Zhang S, Zhou K, Pan X, Lin Y, Peng J, Qin J, Ke Z, Han Y, Chen Z, Du X, Li W, Wei P, Wang D.   +12 more
europepmc   +1 more source

PLAUR+ Neutrophils Drive Anti‐PD‐1 Therapy Resistance in Patients with Hepatocellular Carcinoma by Shaping an Immunosuppressive Microenvironment

Advanced Science, EarlyView.
The present study reveals that PLAUR+ neutrophils are enriched in immunotherapy non‐responders and correlate with poor prognosis. PLAUR+ neutrophils dictate immunotherapy resistance in hepatocellular carcinoma by forming an immunosuppressive tumor microenvironment characterized by CD8+ T cell exclusion and macrophage‐dependent immune suppression.
Shaoqing Liu, Yanzhao Zhou, Gaoxiang Li, Bingwen Zhu, Fang Wu, Jinxue Zhou, Xiaobing Chen, Bo Qin, Yanxia Gao, Fazhan Wang, Yong Jiang, Wenxin Xu   +11 more
wiley   +1 more source

Complete mitochondrial genome of Houttuynia cordata sheds light on the evolution of complex structural features in early angiosperms. [PDF]

BMC Plant Biol
Huang Y, Zhu B, Hu S, Shi W, Liu Y, Lin Q, Wang S, Yang J, Shi C.   +8 more
europepmc   +1 more source

Modulating Macrophage–Nucleus Pulposus Cell Crosstalk via Sequential Drug Delivery Attenuates Disc Degeneration

Advanced Science, EarlyView.
The G‐CS/MSN drug delivery system enhances intervertebral disc repair through sequential drug release. Abstract Intervertebral disc degeneration (IDD) is characterized by an inflammatory environment and dysregulation of the extracellular matrix metabolism (ECM).
Xiangzhen Kong, Rui Hu, Peng Zhang, Qi Li, Kangle Song, Hanwen Gu, Jihui Zheng, Shen Liu, Liang Liu, Lin Jin, Lei Cheng, Chengwei Li, Zhijian Wei   +12 more
wiley   +1 more source

Complete Mitochondrial Genome Characterization and Phylogenomics of the Stingless Bee, <i>Heterotrigona itama</i> (Apidae: Meliponini). [PDF]

Insects
Duangphakdee O, Poolprasert P, Rattanawannee A.   +2 more
europepmc   +1 more source

Rapamycin Alleviates Heart Failure Caused by Mitochondrial Dysfunction and SERCA Hypoactivity in Syntaxin 12/13 Deficient Models

Advanced Science, EarlyView.
Rapamycin alleviates heart failure via TFEB and CaMKII pathways in Syntaxin 12/13 deficient models. Stx12 deficiency causes heart failure via impaired iron trafficking to mitochondria, reducing respiratory complexes and sarcoplasmic reticulum Ca2+‐ATPase (SERCA).
Run‐Zhou Yang, Fang Li, Jiao Liu, Shu‐Ang Li, Dan‐Hua Liu, Zhuanbin Wu, Pei‐Pei Liu, Wenju Liu, Bin Zhou, Cizhong Jiang, Haibing Zhang, Ying Yu, Jian‐Sheng Kang   +12 more
wiley   +1 more source

Complete mitochondrial genome of the brain coral <i>Platygyra daedalea</i> (Ellis & Solander, 1786). [PDF]

Mitochondrial DNA B Resour
Chang X, Chen X, Ke S, Li X, Chen K, Li Y, Bao L, Hu J, Wang S, Bao Z.   +9 more
europepmc   +1 more source

Nanoplastics Enhance Transmembrane Transport and Uptake of Carcinogens: Transcriptional Changes and the Effects of Weathering

Advanced Science, EarlyView.
Nanoplastics exposed to defined weathering conditions are systematically investigated as vectors for polycyclic aromatic hydrocarbons (PAHs). This investigation demonstrates significant potential for enhancing PAH uptake and transport in an intestinal membrane model.
Erik B. Schiferle, Saatwik Suman, Katherine R. Steffen, Koustav Kundu, Aniqa N. Islam, Björn M. Reinhard   +5 more
wiley   +1 more source

The complete mitochondrial genome of the common dace Leuciscus leuciscus (Teleostei: Leuciscidae). [PDF]

Mitochondrial DNA B Resour
Haÿ V, Pividori R, Dettai A, Delling B, Denys GPJ.   +4 more
europepmc   +1 more source

LncRNA Foxo6os as a Novel “ Scaffold” Mediates MYBPC3 in Combating Pathological Cardiac Hypertrophy and Heart Failure

Advanced Science, EarlyView.
Schematic overview showing that forkhead box O6, opposite strand (Foxo6os) acts as a “scaffold”, directly binding myosin‐binding protein‐C (MYBPC3) and recruiting protein kinase C (PKC‐α) to mediate site‐specific phosphorylation of MYBPC3. This post‐translational modification supports cardiac contraction by regulating L‐type Ca2+ channels, especially ...
Jie Sheng, Qin Lin, Yizhuo Sun, Yilei Meng, Sangyu Hu, Huaming Cao, Fang Lin, Yuping Zhu, Luying Peng, Li Li   +9 more
wiley   +1 more source