Results 341 to 350 of about 451,629 (401)

The first report on complete mitochondrial genome of <i>Murina yushuensis</i> (Chiroptera: Vespertilionidae) and its phylogenetic analysis. [PDF]

Mitochondrial DNA B Resour
Shi H, Huang T, Fan X, Wang X, Yu W, Fu X, Wu Y.   +6 more
europepmc   +1 more source

DNMT2‐m5C‐ACLY Axis Promotes Lenvatinib Resistance in Hepatocellular Carcinoma Through Histone Acetylation‐Mediated Notch Pathway

Advanced Science, EarlyView.
Lenvatinib resistance poses a major challenge in advanced hepatocellular carcinoma (HCC). This study reveals that DNMT2 upregulation is a key driver, which stabilizes ACLY mRNA via m5C modification and activates the Notch signaling pathway. Crucially, combining ACLY inhibitors with lenvatinib overcomes resistance and suppresses tumors, offering a ...
Shiguang Yang, Jie Li, Shengwei Mao, Xuhui Zhao, Douwaner Liu, Jiafeng Chen, Jialu Fu, Yichao Bu, Xiaoling Wu, Shaoqing Liu, Qifeng Yu, Qiongzhu Dong, Zheng Tang, Yuan Fang, Yinghong Shi   +14 more
wiley   +1 more source

Complete mitochondrial genome of the ectomycorrhizal fungus <i>Suillus collinitus</i> (Suillaceae, Boletales). [PDF]

Mitochondrial DNA B Resour
Liu WX, Zhang S, Zhang YJ.
europepmc   +1 more source

Connexin43 Deficiency Leads to Ventricular Arrhythmias by Reprogramming Proline Metabolism

Advanced Science, EarlyView.
The study demonstrated that connexin43 (Cx43) knockout caused arrhythmic phenotype and decreased proline content in vitro and in vivo. Mechanistically, Cx43 interacts with the amino acid transporter SNAT2 (sodium‐dependent neutral amino acid transporter), and its deficiency disrupts proline transport and metabolism.
Hangying Ying, Hangping Fan, Yunhe Wang, Ruhong Jiang, Dongsheng Cai, Hui Cheng, Hao Wang, Chenyang Jiang, Ping Liang   +8 more
wiley   +1 more source

The Complete Mitochondrial Genome of the Pest Beetle <i>Latheticus oryzae</i>: Assembly, Annotation, and Phylogenetic Analysis. [PDF]

Ecol Evol
Xu S, Cheng L, Hu W, Gao Y, Cheng Q, Lv J.   +5 more
europepmc   +1 more source

The FOXC2‐LAMA4 Axis Orchestrates Vasculogenic Mimicry and Immunosuppressive Niche Formation to Drive Metastatic Cascade in Renal Cell Carcinoma

Advanced Science, EarlyView.
Advanced clear cell renal cell carcinoma metastasis is driven by a FOXC2+ tumor subpopulation. These cells execute vasculogenic mimicry for dissemination and secrete LAMA4. LAMA4 engages macrophage ITGA6, activating the STAT6/GATA3 axis to polarize macrophages into a pro‐metastatic, immunosuppressive phenotype.
Jiaxi Yao, Tong Xu, Chengyuan Wang, Chenyuan Wang, Junfeng Xie, Rui Zheng, Ke Wang, Xingzuo Jiang, Zewei Hu, Hongwei Jing, Lin Li, Tao Liu   +11 more
wiley   +1 more source

The complete mitochondrial genome of <i>Butis koilomatodon</i> (Bleeker, 1849) (Gobiiformes: Butidae) and its phylogenetic analysis. [PDF]

Mitochondrial DNA B Resour
He ZJ, Feng W, Hu YT, Lu CS, Luo SJ, Chen WF, Wang JJ.   +6 more
europepmc   +1 more source

The first complete mitochondrial genome sequence of the common Baya weaverbird ( Ploceus philippinus ) from southern India

Venkatesh Nagarajan‐Radha, Subanithi-Purnima Murugan, Paramanantha Swami Doss Devaraj   +2 more
openalex   +1 more source

Targeting the GPX4–FUNDC1 Interaction with Magnesium Lithospermate B Attenuates Sepsis‐Associated Lung Injury

Advanced Science, EarlyView.
The diagram depicts the endothelial‐protective mechanism of magnesium lithospermate B (MLB) in sepsis‐associated lung injury. MLB binds GPX4 at Gly79, disrupts its interaction with FUNDC1, prevents mitophagy‐mediated GPX4 degradation, restores mitophagic flux, reduces ROS, and limits ferroptosis.
Zhixi Li, Chang Liu, Zhaoxue Ma, Dongyou Zheng, Renkai Wang, Yongjing Yu, Guangmin Chen, Chenglong Li, Yue Bu, Hang Cao, Bing Zhang   +10 more
wiley   +1 more source

Complete mitochondrial genome of <i>Pseudocentema liui</i> (Phasmatodea; Lonchodidae）. [PDF]

Microbiol Resour Announc
Luo T, Luo H, Guo J, Bian X.
europepmc   +1 more source