Results 71 to 80 of about 307,893 (296)

Plasmodium vivax-like genome sequences shed new insights into Plasmodium vivax biology and evolution [PDF]

open access: yes, 2018
Although Plasmodium vivax is responsible for the majority of malaria infections outside Africa, little is known about its evolution and pathway to humans. Its closest genetic relative, P.
Arnathau, Céline   +15 more
core   +5 more sources

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Complete mitochondrial genome of Favonigobius gymnauchen (BLEEKER, 1850) assembled from next-generation sequencing data

open access: yesMitochondrial DNA. Part B. Resources, 2019
The complete mitochondrial genome of Favonigobius gymnauchen was sequenced. The circular mitochondrial genome is 16,480 bp and consists of 13 protein-coding, 2 ribosomal RNAs, and 13 transfer RNA genes (GenBank accession no. MN194589). Results of maximum
Hyunbin Jo   +3 more
doaj   +1 more source

Complete mitochondrial genome of Gnathostoma binucleatum

open access: yesMicrobiology Resource Announcements
This report describes the mitochondrial genome of the parasite Gnathostoma binucleatum (G. binucleatum), which was obtained from naturally infected freshwater fish in Sinaloa, Mexico (22°46'00.1″N 105°40'21.8″W). G. binucleatum is responsible for human gnathostomiasis and is endemic to Mexico.
Sylvia Paz Diaz-Camacho   +9 more
openaire   +2 more sources

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

The complete mitochondrial genome of freshwater mussel Nodularia douglasiae (Unionidae) from Lake Kasumigaura, Japan, and its phylogenetic analysis

open access: yesMitochondrial DNA. Part B. Resources, 2019
We have sequenced the female type (F-type) mitochondrial genome of Nodularia douglasiae (Unioninae, Unionidae, Unionida, Bivalvia) from Lake Kasumigaura, Japan, and inferred the Unioninae phylogeny using complete mitochondrial genome sequences.
Yohei Fukata, Masayuki Iigo
doaj   +1 more source

Puntius denisonii mitochondrion, complete genome [PDF]

open access: yes, 2013
The complete mitochondrial genome of Puntius ...
Baby, A   +8 more
core  

Combined flow cytometry and high-throughput image analysis for the study of essential genes in Caenorhabditis elegans [PDF]

open access: yes, 2018
Background: Advances in automated image-based microscopy platforms coupled with high-throughput liquid workflows have facilitated the design of large-scale screens utilising multicellular model organisms such as Caenorhabditis elegans to identify genetic
Artal Sanz, Marta   +10 more
core   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

open access: yesFEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti   +3 more
wiley   +1 more source

Complete mitochondrial DNA and phylogenetic study of qionglai native black chicken

open access: yesMATEC Web of Conferences, 2016
The complete mitochondrial genome sequence of the qionglai black chicken was measured by PCR-based methods, the molecular characterization and phyletic evolution analyzed in detail.
Hu Yaodong   +3 more
doaj   +1 more source

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