Results 61 to 70 of about 411,877 (267)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Complete convergence and complete moment convergence for negatively dependent random variables under sub-linear expectations

open access: yesFilomat, 2020
This paper we study and establish the complete convergence and complete moment convergence theorems under a sub-linear expectation space. As applications, the complete convergence and complete moment convergence for negatively dependent random variables with CV (exp (ln? |X|)) < ?, ?
Wu, Qunying, Jiang, Yuanying
openaire   +2 more sources

Complete Moment Convergence for Arrays of Rowwise φ-Mixing Random Variables

open access: yesAbstract and Applied Analysis, 2014
We investigate the complete moment convergence for maximal partial sum of arrays of rowwise φ-mixing random variables under some more general conditions. The results obtained in the paper generalize and improve some known ones.
Lulu Zheng, Yanfang Liu, Xuejun Wang
doaj   +1 more source

Prognostic Impact of European LeukemiaNet Genetic Risk Stratification System in Adult Patients With Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha   +4 more
wiley   +1 more source

Complete Convergence and Complete Moment Convergence for Maximal Weighted Sums of Extended Negatively Dependent Random Variables [PDF]

open access: yesActa Mathematica Sinica, English Series, 2018
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +3 more sources

Complete convergence of randomly weighted END sequences and its application

open access: yesJournal of Inequalities and Applications, 2017
We investigate the complete convergence of partial sums of randomly weighted extended negatively dependent (END) random variables. Some results of complete moment convergence, complete convergence and the strong law of large numbers for this dependent ...
Penghua Li, Xiaoqin Li, Kehan Wu
doaj   +1 more source

The Vanishing Moment Method for Fully Nonlinear Second Order Partial Differential Equations: Formulation, Theory, and Numerical Analysis [PDF]

open access: yes, 2011
The vanishing moment method was introduced by the authors in [37] as a reliable methodology for computing viscosity solutions of fully nonlinear second order partial differential equations (PDEs), in particular, using Galerkin-type numerical methods such
Feng, Xiaobing, Neilan, Michael
core  

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

open access: yesAging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang   +3 more
wiley   +1 more source

Complete and complete moment convergence for weighted sums of ρ̃-mixing random variables [PDF]

open access: yesJournal of Mathematical Inequalities, 2018
Summary: In this paper, we establish complete convergence results and a complete moment convergence result and prove the equivalence of them for weighted sums of \(\tilde{\rho}\)-mixing random vari ables. Our results generalize and improve the results of \textit{L. E. Baum} and \textit{M. Katz} [Trans. Am. Math. Soc. 120, 108--123 (1965; Zbl 0142.14802)
Feng, Fengxiang   +2 more
openaire   +2 more sources

Bottom and Charm Mass Determinations with a Convergence Test

open access: yes, 2015
We present new determinations of the MS-bar charm quark mass using relativistic QCD sum rules at O(alpha_s^3) from the moments of the vector and the pseudoscalar current correlators.
Dehnadi, Bahman   +2 more
core   +1 more source

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