Results 161 to 170 of about 9,187,062 (277)

Complete mitochondrial DNA sequences of <i>Eliurus webbi</i> and <i>Eliurus minor</i>, endemic tufted-tailed rats in Madagascar. [PDF]

Mitochondrial DNA B Resour
Paietta EN, Randrianarisoa SF, Razanamahenina TT, Ramboninarimalala A, Raherinirina TG, Raveloson L, Finley NL, Yoder AD, Baitchman E, Varsani A, Johnston RA.   +10 more
europepmc   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Ingestible active capsule for gastrointestinal microbiome sampling. [PDF]

Biomed Microdevices
Shahadha MH, Voigt A, Gruner D, Marschner U, Le Floch M, Hampe J, Brauer F, Schostek S, Luniak M, Bock K, Richter A.   +10 more
europepmc   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Acute intrathoracic sigmoid volvulus in major congenital diaphragmatic eventration: a rare thoracoabdominal emergency in an 18-year-old. [PDF]

J Surg Case Rep
Martz N, Al Zreibi C, Reverdito G, Mariani A, Meatchi T, Le Pimpec-Barthes F.   +5 more
europepmc   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

Bandwidth broadening in cavity-type sound-absorbing metamaterials via additional equivalent stiffness. [PDF]

Sci Rep
Wang LB, Wu JH, Zhang JF.
europepmc   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

First Complete Morphological Description of Schistosoma Reflexum in a Llama. [PDF]

Vet Med Sci
Luginbühl C, Hiller LA, Van der Vekens E, Weber BA, Drögemüller C, Zanolari P, Gurtner C, Jacinto J.   +7 more
europepmc   +1 more source