Results 171 to 180 of about 9,187,062 (277)

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Granular cell tumors of the neurohypophysis with atypical imaging features: a case report and literature review. [PDF]

BMC Neurol
Li A, Gao P, Tian W, Zhou M, Zeng J, Chen M.   +5 more
europepmc   +1 more source

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

FEBS Open Bio, EarlyView.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca, Anna Tricarico, Martina Furfaro, Priyam Ghosh, Ennio Prosperi, Lucia Anna Stivala, Ornella Cazzalini   +6 more
wiley   +1 more source

Management of Intrathoracic Huge Meningocele in a Case of Neurofibromatosis Type-1, Report of a Case and Review of the Literature. [PDF]

Int Med Case Rep J
Mousavi SR, Farrokhi MR, Salehpour F, Fallahi MJ, Ghaedian T, Rezaei N, Haghighatafshar M, Hosseini K, Eghbal K, Jangi Aghdam H, Gerami MH, Amir Shahpari Motlagh M.   +11 more
europepmc   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

FEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde, Unai Alduntzin, Gorka Prieto, Ugo Mayor   +3 more
wiley   +1 more source

Methodological framework for a user-centered, structured, and digitized training program for exoskeleton pilots in CYBATHLON preparation. [PDF]

J Neuroeng Rehabil
Dobler N, Ortelt C, Rieger T, Schneidewind L.   +3 more
europepmc   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Current Models of Plastic Surgery Training in Sub-Saharan Africa: A Review From 2018 to 2022. [PDF]

Plast Reconstr Surg Glob Open
Soltani H, Nthumba J, Figueroa A, Wester J, Elegbede K, Allison SG, Tjinjeka U, Gosain AK.   +7 more
europepmc   +1 more source

Complete in All Its Parts

, 1998
Kathy Penningroth, Lee Anderson
openaire   +1 more source

Part O, Arthropoda 1, Complete Volume

Treatise on Invertebrate Paleontology, 1959
H. J. Harrington, J. M. Weller, B. F. Howell, H. B. Whittington, Klaus Sdzuy, Herta Schmidt, C. J. Stubblefield, Rudolf Richter, Emma Richter, Christina Lochman-Balk, Franco Rasetti, Lief Størmer, Gunnar Henningsmoen, Christian Poulsen, R. C. Moore, Valdar Jaanusson, Ronald Tripp, Wolfgang Struve   +17 more
openaire   +1 more source