Results 81 to 90 of about 14,386,138 (308)
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Pengkajian Penerapan Teknik Budidaya Rhizophora mucronata dengan Stek Hipokotil
Research on the vegetative propagation of Rhizophora mucronata using hypocotyl cutting sistem was carried out at Faculty of Forestry, Bogor Agricultural University.
Neni Mulyani +2 more
doaj
Six enzymes from mayapple that complete the biosynthetic pathway to the etoposide aglycone
Transplanting the wisdom of the mayapple Etoposide, a topoisomerase inhibitor, is used to treat various cancers. However, etoposide isn't that easy to get. Its precursor comes from the very slow-growing mayapple plant. Lau and Sattely used bioinformatics,
Warren Lau, Elizabeth S. Sattely
semanticscholar +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Aiming at the problems of high data repeatability, low utilization rate and low construction accuracy of the damaged part model in the remanufacturing process of helical gear parts, a modeling method for constructing a complete part model using local ...
Xiaoling Wei, Yi Meng, Xiujun Sun
doaj
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
A case of midline cleft of the lower lip with cleft of the mandible and complete duplication of the tongue is reported here. Median cleft of the lower lip, mandible and bifid tongue with ankyloglossia is reported in the literature, but complete ...
Nirmal C Bhattacharyya +3 more
doaj +1 more source
Although Escherichia coli is the most widely studied bacterial model organism and often considered to be the model bacterium per se, its type strain was until now forgotten from microbial genomics.
Jan P. Meier-Kolthoff +18 more
semanticscholar +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source

