Results 31 to 40 of about 7,985,327 (252)

Neoadjuvant Chemotherapy in Luminal A Breast Carcinoma: Histopathological Evidence of Limited Impact

The Egyptian Journal of Histology
Introduction. Breast cancer is the most frequently diagnosed malignancy among women worldwide, including in Saudi Arabia. Aim of work: This retrospective study evaluated the histopathological alterations in luminal A breast carcinomas following ...
Elham Saad, Muhammad Atteya, Ahmed El Fouhil, Eman Elkordy, Rasha Salih, Raeesa Mohammed, Maha Arafah   +6 more
doaj   +1 more source

Complete pathological response (ypT0N0M0) after preoperative chemotherapy alone for stage IV rectal cancer [PDF]

, 2014
Complete pathological response occurs in 10-20% of patients with rectal cancer who are treated with neoadjuvant chemoradiation therapy prior to pelvic surgery.
Theodoros Thomopoulos, Thomopoulos, Theodoros, Toso, Christian, Mentha, Gilles, Gilles Mentha, Naiken, Surennaidoo, Pascal Gervaz, Rubbia-Brandt, Laura, Surennaidoo P Naiken, Gervaz, Pascal, Morel, Philippe, Christian Toso, Arnaud Roth, Philippe Morel, Roth, Arnaud, Laura Rubbia-Brandt   +15 more
core   +2 more sources

Ovarian Sex Cord Stromal Tumors in Children and Adolescents—The European Standard Clinical Practice Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT As part of the European Cooperative Study Group for Paediatric Rare Tumours initiative, we developed standard clinical practice guidelines for ovarian sex cord stromal tumors, based on comprehensive national and international cohort analyses, literature review, and a final expert consensus conference.
Dominik T. Schneider, Kris‐Ann Schultz, Nora Schnitzler, Michael Abele, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Ines B. Brecht, Maja Cesen, Andrea Ferrari, Michaela Kuhlen, Malgorzata A. Krawczyk, Ricardo Lopez‐Almaraz, Yves Reguerre, Calogero Virgone, Daniel Orbach   +15 more
wiley   +1 more source

Comparative Drug Response Profiling in Neuroblastoma Cell Lines and Patient‐Derived Tumor Organoids

Pediatric Blood &Cancer, EarlyView.
ABSTRACT High‐risk neuroblastoma remains a leading cause of pediatric cancer mortality, and improved preclinical models are needed to guide therapeutic developments. We screened seven high‐risk neuroblastoma cell lines and three patient‐derived tumor organoids with 528 compounds alongside bone marrow controls, and compared them with external datasets ...
Krzysztof Wierbiłowicz, Se Whee Sammy Park, Aironas Los, Ernest Liu, Nona Struyf, Tom Erkers, Sören Lehmann, Jan J. Molenaar, Jakob Stenman, Olli Kallioniemi, Päivi Östling, Brinton Seashore‐Ludlow, Kasper Karlsson   +12 more
wiley   +1 more source

The Role of Magnetic Resonance Imaging in Predicting Pathological Complete Response in Breast Cancer Patients Receiving Neoadjuvant Chemotherapy [PDF]

Objective: Neoadjuvant chemotherapy (NACT) has been used more frequently in the treatment of non-metastatic breast cancer. Achieving a pathological complete response (pCR) after NACT provides us with information about the prognosis of the disease.
Emre Özge, Rıza Umar Gürsu, İlkay Gültürk, Çiğdem Usul, Emine Sevcan Ata, Melis Baykara Ulusan, Bünyamin Güney, Özgür Han   +7 more
core   +1 more source

Preoperative chemoradiation in carcinoma esophagus: Experience from a tertiary cancer center in India

Indian Journal of Medical and Paediatric Oncology, 2018
Background: Esophageal cancer is the fourth most common cause of cancer-related deaths in India. In 2012, the CROSS trial evaluated the benefit of induction therapy using weekly carboplatin-paclitaxel with 41.4 Gy radiation versus surgery alone ...
Harjot Kaur Bajwa, Rohith Singareddy, Mahendra M Reddy, Krishnam A Raju, Subramanyeshwar T Rao, Senthil J Rajappa   +5 more
doaj   +1 more source

The implications of a pathological complete response of the primary tumour after neoadjuvant chemotherapy for breast cancer on axillary surgery

Journal of the Egyptian National Cancer Institute, 2021
Background Management of the node-positive axilla after neoadjuvant chemotherapy is controversial. The aim of this study is to predict the group of patients who may require a less invasive approach for axillary management. One possible group are patients
Mina M. G. Youssef, Ahmed A. Metwally, Tamer M. Manie   +2 more
doaj   +1 more source

Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin, Sheila K. Pierson, Kelley C. Dacus, Mateo Sarmiento Bustamante, Saishravan Shyamsundar, Larissa Borys, Kayla McHugh, Abiola Irvine, Yoojin Jo, Adam Bagg, Mary Jo Lechowicz, Daisy Alapat, Amy Chadburn, Megan S. Lim, Gordan Srkalovic, Frits van Rhee, David C. Fajgenbaum, Joshua D. Brandstadter   +17 more
wiley   +1 more source

Lymph node ratio is a prognostic indicator for locally advanced gastric cancer after neoadjuvant immunochemotherapy

BMC Gastroenterology
Objective The efficacy of lymph node ratio (LNR) as a prognostic indicator in locally advanced gastric cancer (LAGC) patients underwent radical resection after neoadjuvant immunochemotherapy (NICT) remains to be demonstrated. The objective of the current
Pei Zhou, Xiong Sun, Liwu Zeng, Xinyu Zeng, Gengchen Xie, Xinghua Liu, Kaixiong Tao, Peng Zhang   +7 more
doaj   +1 more source

Chemotherapy for Spinal Cord Intramedullary Pediatric Low‐Grade Glioma—A Systematic Literature Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric intramedullary low‐grade gliomas (PIMLGGs) are rare neoplasms that present unique clinical and management challenges. Although surgery remains the primary tool for tissue diagnosis and decompression, complete gross‐total resection is frequently unfeasible due to the infiltrative nature of these lesions.
Olga M. Sergeenko, Segev Gabay, Jonathan Roth, Amit Ringel, Rina Dvir, Shlomi Constantini   +5 more
wiley   +1 more source