Results 51 to 60 of about 1,456,287 (196)

DCE-MRI and parametric imaging in monitoring response to neoadjuvant chemotherapy in breast carcinoma : a preliminary report [PDF]

, 2018
Purpose: Neoadjuvant chemotherapy is recommended in patients with locally advanced breast cancer. Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) enables evaluation of the tumour neovasculature that occurs prior to any volume change, which
Fotedar, Vikas, Seam, Rajeev K., Sharma, Anjna, Sharma, Mukesh, Sharma, Sanjiv, Sood, Shikha   +5 more
core   +1 more source

Clinico-pathological predictors of clinical complete response in rectal cancer

Cancer Treatment and Research Communications, 2022
Prediction of clinical complete response in rectal cancer before neoadjuvant chemo-radiotherapy treatment enables treatment selection. Patients predicted to have complete response could have chemo-radiotherapy, and others could have additional doublet chemotherapy at this stage of their treatment to improve their overall outcome. This work investigates
P. Mbanu, E. Vasquez Osorio, H. Mistry, L. Malcomson, S. Yousif, M. Aznar, R. Kochhar, M. Van Herk, A.G. Renehan, M.P. Saunders   +9 more
openaire   +3 more sources

Phase II study of preoperative bevacizumab, capecitabine and radiotherapy for resectable locally-advanced rectal cancer [PDF]

, 2017
Background: to evaluate whether the addition of bevacizumab (BVZ) to capecitabine-based chemoradiotherapy in the preoperative treatment of locally advanced rectal cancer (LARC) improves efficacy measured by the pathological complete response (pCR) rate ...
Biondo, Sebastián, Cambray i Amenós, Maria, Figueras i Amat, Agnès, García Martin, Margarita, Kreisler, Esther, Lema, Laura, Losa Gaspà, Ferran, Martínez Villacampa, Mercedes, Navarro-Pérez, Valentin, Pisa, Aleydis, Salazar Soler, Ramón, San Juan, Xavier, Santos, Cristina, Soler, Gemma, Teulé-Vega, Àlex, Viñals Canals, Francesc   +15 more
core   +1 more source

Neoadjuvant chemoradiation therapy and pathological complete response in rectal cancer [PDF]

Gastroenterology Report, 2015
The management of rectal cancer has evolved significantly in the last few decades. Significant improvements in local disease control were achieved in the 1990s, with the introduction of total mesorectal excision and neoadjuvant radiotherapy. Level 1 evidence has shown that, with neoadjuvant chemoradiation therapy (CRT) the rates of local recurrence can
Ferrari, Linda, Fichera, Alessandro
openaire   +2 more sources

Primary synovial sarcoma of the kidney: a case report of complete pathological response at a Lebanese tertiary care center

BMC Urology, 2018
BackgroundPrimary synovial sarcoma of the kidney is a rare type of soft tissue sarcoma. Its presenting features can resemble those of other renal tumors; rendering its early diagnosis, a dilemma. Several cases of renal synovial sarcoma have been reported
Alissar El Chediak, D. Mukherji, S. Temraz, S. Nassif, Sara Sinno, R. Mahfouz, A. Shamseddine   +6 more
semanticscholar   +1 more source

Development and validation of the new HER2DX assay for predicting pathological response and survival outcome in early-stage HER2-positive breast cancer

EBioMedicine, 2022
Summary Background Both clinical and genomic data independently predict survival and treatment response in early-stage HER2-positive breast cancer. Here we present the development and validation of a new HER2DX risk score, and a new HER2DX pathological ...
A. Prat, V. Guarneri, T. Pascual, F. Brasó-Maristany, E. Sanfeliu, L. Paré, F. Schettini, D. Martínez, P. Jares, G. Griguolo, M. Dieci, J. Cortés, A. Llombart-Cussac, B. Conte, M. Marín-Aguilera, N. Chic, J. Puig-Butillé, Antonio Martinez, P. Galván, Yi-Hsuan Tsai, B. González-Farré, A. Mira, A. Vivancos, P. Villagrasa, J. Parker, P. Conte, C. Perou   +26 more
semanticscholar   +1 more source

Chemotherapy-Response Monitoring of Breast Cancer Patients Using Quantitative Ultrasound-Based Intra-Tumour Heterogeneities [PDF]

, 2017
© 2017 The Author(s). Anti-cancer therapies including chemotherapy aim to induce tumour cell death. Cell death introduces alterations in cell morphology and tissue micro-structures that cause measurable changes in tissue echogenicity.
A Ahmed, A Guimond, A Sadeghi-Naini, A Sadeghi-Naini, A Sadeghi-Naini, A Sadeghi-Naini, A Sadeghi-Naini, A Sadeghi-Naini, A Sadeghi-Naini, B Banihashemi, B Fisher, B Ganeshan, BS Garra, BS Pio, BT Hennessy, C-P Chou, D Sethi, DA Mankoff, EJ Feleppa, EJ Feleppa, F Tixier, FJ Esteva, FL Lizzi, FT D’Astous, G Berger, G Minckwitz von, GJ Czarnota, GJ Czarnota, GN Hortobagyi, H Haibo, H Tadayyon, H Tadayyon, H Tadayyon, HC Kim, HM Kuerer, II Wistuba, J Czernin, JB Nikas, JPB O’Connor, K Brindle, K Sikora, K Suzuki, KA Wear, KM Brindle, KN Ogston, L Sannachi, LX Yao, M Dowsett, M Vaidya, MF Insana, ML Oelze, ML Oelze, N Duric, O Falou, O Falou, QH Huang, R Tiling, RM Haralick, RM Vlad, RM Vlad, SH Giordano, SH Giordano, SJ Cleator, SM Scholl, T Cover, TJ Larkin, U McDermott, V Goh, V Guarneri, X Li, Y Labyed   +70 more
core   +2 more sources

Pathological complete response in younger and older breast cancer patients [PDF]

Archives of Medical Science, 2012
Pathologic complete response (pCR) after neoadjuvant systemic treatment for inoperable locally advanced breast cancer is defined as complete microscopic disappearance of invasive cancer in both the breast and axilla in the postoperative specimen. The aim of the study was to characterize the groups of younger (≤ 40 years old) and older (≥ 70 years old ...
Kołacińska, Agnieszka, Chałubińska, Justyna, Błasińska-Morawiec, Maria, Dowgier-Witczak, Izabela, Fendler, Wojciech, Kordek, Radzisław, Morawiec, Zbigniew   +6 more
openaire   +2 more sources

A case of synchronous bilateral breast cancer with different pathological responses to neoadjuvant chemotherapy with different biological character [PDF]

, 2013
We report a case of synchronous locally advanced bilateral breast cancer with different pathological responses to neoadjuvant chemotherapy with different biological character.
Hirotaka Iwase, Mitsuhiro Hayashi, Noboru Takata, Yutaka Yamamoto   +3 more
core   +1 more source

Pharmacometabolomics study identifies circulating spermidine and tryptophan as potential biomarkers associated with the complete pathological response to trastuzumab-paclitaxel neoadjuvant therapy in HER-2 positive breast cancer

OncoTarget, 2016
Defining biomarkers that predict therapeutic effects and adverse events is a crucial mandate to guide patient selection for personalized cancer treatments.
G. Miolo, E. Muraro, D. Caruso, D. Crivellari, A. Ash, S. Scalone, D. Lombardi, F. Rizzolio, A. Giordano, G. Corona   +9 more
semanticscholar   +1 more source