Results 21 to 30 of about 5,241,947 (282)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background B‐cell lymphoblastic lymphoma (B‐LBL) represents a rare variety of non‐Hodgkin lymphoma, with limited research on its biology, progression, and management. Methods A retrospective analysis was performed on the clinical characteristics of 256 patients aged ≤18 years who received treatment under the China Net Childhood Lymphoma (CNCL)‐
Zhijuan Liu +20 more
wiley +1 more source
Hyperbolic Dehn filling in dimension four
, 2017 We introduce and study some deformations of complete finite-volume hyperbolic four-manifolds that may be interpreted as four-dimensional analogues of Thurston's hyperbolic Dehn filling.
Martelli, Bruno, Riolo, Stefano
core +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Introduction Cognitive impairment and exercise intolerance are common in dialysis patients. Cerebral perfusion and oxygenation play a major role in both cognitive function and exercise execution; HD session per se aggravates cerebral ischemia in this population. This study aimed to compare cerebral oxygenation and perfusion at rest and in mild
Marieta P. Theodorakopoulou +10 more
wiley +1 more source
Three-manifolds with many flat planes
, 2016 We discuss the rigidity (or lack thereof) imposed by different notions of having an abundance of zero curvature planes on a complete Riemannian 3-manifold.
Bettiol, Renato G., Schmidt, Benjamin
core +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Introduction Patients with ovarian cancer often present with massive ascites, leading to significant protein loss during surgical procedures. Although cell‐free concentrated ascites reinfusion therapy (CART) is used in palliative settings to mitigate protein loss, its application in intraoperative settings remains unexplored.
Yutaka Yoneoka +7 more
wiley +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
On the Hamilton's isoperimetric ratio in complete Riemannian manifolds of finite volume
, 2020 We contribute to an original problem studied by Hamilton and others, in order to understand the behaviour of maximal solutions of the Ricci flow both in compact and non-compact complete orientable Riemannian manifolds of finite volume.
Nardulli, Stefano, Russo, Francesco G.
core
Complete bounded $\lambda$-hypersurfaces in the weighted volume-preserving mean curvature flow
, 2017 In this paper, we study the complete bounded $\lambda$-hypersurfaces in weighted volume-preserving mean curvature flow. Firstly, we investigate the volume comparison theorem of complete bounded $\lambda$-hypersurfaces with $|A|\leq\alpha$ and get some ...
Chen, Qing, Fang, Yi, Zhu, Yecheng
core +1 more source
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source