Results 101 to 110 of about 6,845,583 (296)
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
C'est par où la piscine?! Retrouvez l'album souvenir public de MAPS 10 en ligne ici et l'album complet sur demande (réservé aux participants) Lisez aussi le compte-rendu de MAPS 10 du point de vue d'un archéologue et d'un ...
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Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
From Rotations to Unitaries: Reversible Quantum Processes and the Emergence of the SU(2)−SO(3) Homomorphism [PDF]
We present an operational reconstruction of the well-known two-to-one homomorphism between the groups SU(2) and SO(3), grounded in the physical description of quantum state preparation and evolution.
V.G Valle, B.F. Rizzuti
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Extremal equation for optimal completely positive maps [PDF]
REVTeX, 7 pages, 2 figures, important reference ...
openaire +2 more sources
Tourist map with roads emphasized. Relief shown by gradient tints and spot heights. Depths shown by gradient tints. Includes notes, indexes of places, publisher's index map, publisher's map list, and color illustrations.Color;1:2,400 ...
International Travel Maps (Firm);
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This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
MAPS 13 est une École Thématique du CNRS et a reçu le soutien de l'INSHS. Nous prendrons nos quartiers pour 5 jours, du 21 au 26 juin 2020, à Colleville-sur-Mer (Normandie), près des plages du débarquement.
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