Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Addressing Data Quality Challenges in Lung Cancer Data Within the Observational Medical Outcomes Partnership Common Data Model: Observational Study. [PDF]
Declerck J +4 more
europepmc +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
LLMs as emerging tools for understanding and managing bone metastasis and cancer-induced bone pain. [PDF]
Li J +8 more
europepmc +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
"Assessment of an EMR-integrated Onco-Insight hospital-based cancer registry system for data completeness and data entry turnaround time at a tertiary care cancer center in India". [PDF]
Oak A +15 more
europepmc +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Performance comparison of large language models for medication counseling in people living with HIV. [PDF]
Huang C, Sun Y, Chen M, Zhang L, Liu W.
europepmc +1 more source
The Influence of Different Gypsum Materials on the Accuracy from Complete Arch Digital Impression
Gyeong-Tak Lee Ki-Baek Kim +1 more
openalex +1 more source

