Results 231 to 240 of about 6,430,501 (374)

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

The complete mitochondrial genome sequence of the pathogenic yeast Candida (Torulopsis) glabrata [PDF]

, 2002
Romain Koszul, Alain Malpertuy, Lionel Frangeul, Christiane Bouchier, Patrick Wincker, Agnès Thierry, Stéphanie Duthoy, Stéphane Ferris, Christophe Hennequin, Bernard Dujon   +9 more
openalex   +1 more source

Evaluating the quality of social media content on metabolic dysfunction associated steatotic liver disease: An experience from a lower middle-income country. [PDF]

PLoS One
Niriella MA, Wijesingha IP, Prabagar K, Abeynayake D, Jayasena H, Herath PR, Kajendran A, Rishikesavan V, Balendran K, de Silva T, De Silva AP, de Silva HJ.   +11 more
europepmc   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

A clean and complete sample of galaxies in the GAMAII survey equatorial regions, within redshift 0.06.

Glass, David H. W., Sansom, Anne E.
openalex   +1 more source

Complete Genome Sequences of Aerococcus christensenii CCUG 28831 ^T , Aerococcus sanguinicola CCUG 43001 ^T , Aerococcus urinae CCUG 36881 ^T , Aerococcus urinaeequi CCUG 28094 ^T , Aerococcus urinaehominis CCUG 42038 B ^T , and Aerococcus viridans CCUG 4311 ^T [PDF]

, 2016
Derya Carkaci, Rimtas Dargis, Xiaohui Chen Nielsen, Ole Skovgaard, Kurt Fuursted, Jens Jørgen Christensen   +5 more
openalex   +1 more source

Complete Prostatectomy [PDF]

BMJ, 1947
openaire   +2 more sources

Variability in Perceived Healthcare Data Quality Across Tanzanian Regional Referral Hospitals: A Hospital-Based Cross-Sectional Study. [PDF]

Health Sci Rep
Phinias R, Muhanga M, Malago J.
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

An infilled globally complete version of the Dynamically Consistent ENsemble of Temperature at the Earth surface dataset (DCENT): DCENT-I (1850 - present)

Chan, Duo, Chan, Steven C, Siddons, Joseph T, Cable, Archie, Faulkner, Agnieszka, Cornes, Richard C, Kent, Elizabeth C, Gebbie, Geoffrey, Huybers, Peter J   +8 more
openalex   +1 more source