Results 211 to 220 of about 307,001 (266)

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Current state of electronic problems lists in primary care: a rapid scoping review. [PDF]

Fam Pract
Nair R, Bekker I, Singer A, Lau F.
europepmc   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Toward Automating the Summarization of Cancer Pathology Reports Using Large Language Models to Improve Clinical Usability. [PDF]

JCO Clin Cancer Inform
Liu Y, John J, Sarkar S, Zakkar A, Kinkopf P, Teo PT, Abazeed ME.   +6 more
europepmc   +1 more source

Robotic versus laparoscopic TME for rectal cancer: meta-analysis of pathological quality indicators. [PDF]

Tech Coloproctol
Morarasu S, Lunca S, Clancy C, Ong WL, Morpurgo E, Dimofte GM.   +5 more
europepmc   +1 more source

Quality of Drug Allergy Documentation in a Resource-Limited Paper-Based Hospital in Pakistan: Audit of Concordance and Completeness. [PDF]

Healthcare (Basel)
Obeidat A, Ud Din A, Khan MA, Asad Khan A, Atif E, Mazhar MA, Khan MZ, Qazi S.   +7 more
europepmc   +1 more source

Reference Genome Assembly of a Tetraploid Accession of the Tuber Crop Tropaeolum tuberosum. [PDF]

Genome Biol Evol
Ruiz-Mateus D, Scheffler I, Márquez-Cardona MDP, Greb T, Terán W, Hunziker P.   +5 more
europepmc   +1 more source

Comprehensive benchmarking of metagenomic binning tools reveals key factors for improved genome recovery. [PDF]

Nat Commun
Kim J, Kim N, Cha JH, Ma J, Lee I.
europepmc   +1 more source