Has the COVID-19 pandemic enhanced the capacity of rural public health emergency management? Evidence from Jiangsu Province of China. [PDF]
Front Public HealthCao M, Zhang Y.
europepmc +1 more source
Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes
FEBS Open Bio, EarlyView.We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde +3 more
wiley +1 more source
Reply to Hertig-Godeschalk et al. Comment on "Bai et al. Effect of Eccentric Training with Different Durations, Intensities, and Contraction Velocities on Upper Limb Muscle Strength: A Meta-Analysis. <i>Life</i> 2025, <i>15</i>, 456". [PDF]
Life (Basel)Bai Z +5 more
europepmc +1 more source
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
Evaluating international collaboration on horizon scanning for pharmaceuticals: developing key performance indicators for the international horizon scanning initiative. [PDF]
Int J Technol Assess Health CareLeeneman B +3 more
europepmc +1 more source
FEBS Open Bio, EarlyView.Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui +10 more
wiley +1 more source
Benchmarking Generative AI Tools for Interpretation of the WHO TB Mutation Catalogue. [PDF]
BMC Digit HealthMoreno-Molina M +3 more
europepmc +1 more source
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Assessment of the Quality of post-abortion care records in 20 Public Health Facilities in Uganda: What are the gaps and how can we improve quality? [PDF]
PLoS OneAtuyambe LM +9 more
europepmc +1 more source