Results 101 to 110 of about 1,512,917 (302)

A COMPLETION THEOREM FOR COMPLEX VALUED S-METRIC SPACE

open access: yesBarekeng
Any complex valued S-metric space where each Cauchy sequence converges to a point in this space is said to be complete. However, there are complex valued S-metric spaces that are incomplete but can be completed.
Mariatul Kiftiah   +3 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Predictors of ongoing attendance at an Australian publicly funded specialist obesity service

open access: yesObesity Science & Practice
Introduction There is a demand for publicly funded specialist obesity services in Australia. A range of factors can impact on patient attendance which can result in poorer health outcomes.
Louise Brightman   +2 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Social insurance and the completion of the internal market [PDF]

open access: yes
With the completion of the internal market in the EU pressures may arise to diminish social insurance budgets. In a two-country model with an (imperfectly) integrated consumer goods market it is shown that competitive member states use the social ...
Lejour, A.M.
core  

Fishbone type horizontal wellbore completion: A study for pressure behavior, flow regimes, and productivity index

open access: yes, 2019
This paper focuses on studying pressure behavior, flow regimes, and productivity index of oil and gas reservoirs depleted by horizontal wells with a fishbone type completion technology.
Al-Rbeawi, Salam, Artun, Emre
core   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Supporting Doctoral Candidates through Completion and Final Examination

open access: yesEncyclopedia
Completion and final examination comprise the final stages of a doctoral program and represent the culmination of the doctoral candidates’ years of research.
Kirsten Riches-Suman
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

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