Results 41 to 50 of about 14,492,801 (287)

Evidence‐Informed Multidisciplinary Consensus Guidance for the Psychosocial Care of Adolescents With High‐Risk Cancer: Recommendations From the Italian Association of Pediatric Hematology and Oncology

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Adolescents with high‐risk cancer face complex developmental, psychosocial, and ethical challenges that extend beyond disease‐directed treatment. Although international recommendations exist for communication, psychosocial care, pediatric palliative care, survivorship, and shared decision‐making, these have largely evolved within ...
Johanna M. C. Blom, Dorella Scarponi, Giulia Zucchetti, Teresa Perillo, Maria Montanaro, Elisa Marconi, Chiara Rutigliano, Paolo Colavero, Paola Quarello, Marina Bertolotti, Monica Cellini, Carlo Clerici, Maurizio Mascarin, Francesca Bomben, Andrea Ferrari, the expert workgroup   +15 more
wiley   +1 more source

DoReMi: context-based prioritization of linear motif matches [PDF]

PeerJ, 2014
Many protein domains bind to short peptide sequences, called linear motifs. Data on their sequence specificities is sparse, which is why biologists usually resort to basic pattern searches to identify new putative binding sites for experimental follow-up.
Heiko Horn, Niall Haslam, Lars Juhl Jensen   +2 more
doaj   +2 more sources

External and internal complexity of complex adaptive systems [PDF]

Theory in Biosciences, 2004
We introduce concepts of external and internal complexity to analyze the relation between an adaptive system and its environment. We apply this theoretical framework to the construction of models in a cognitive system and the selection between hypotheses through selective observations performed on a data set in a recurrent process and propose a ...
openaire   +3 more sources

Bridging the Loneliness Gap: Depression, Connectivity, and Isolation in Pediatric Oncology Patients and Their Peers

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Loneliness is associated with adverse physical and mental health outcomes and remains understudied in children and adolescents undergoing cancer therapy. Pediatric oncology patients may be at increased risk due to medical isolation and disruption of social networks.
Charlotte N. Stahlfeld, Scott H. Maurer, Michelle D. Watkinson, John Nury, Elise Barberis, Molly C. Mack   +5 more
wiley   +1 more source

Complex adaptive systems and the evolution of reciprocation [PDF]

AIP Conference Proceedings, 1998
Complex adaptive systems play a major role in the theory of reciprocal altruism. Starting with Axelrod's celebrated computer tournaments, a wide variety of computer simulations show that cooperation can evolve in populations of selfish agents, both with direct and indirect reciprocation.
openaire   +4 more sources

Central Nervous System Tumors Among Infants in Canada: A Report From CYP‐C

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) tumors in infants are rare, pose unique clinical challenges, and lack large‐scale evidence‐based data to guide management. This study seeks to describe CNS tumors in Canadian infants and to compare their outcomes with those of older children.
Samuel Sassine, Hallie Coltin, Sylvia Cheng, Lucie Lafay‐Cousin, Vanan Issai Magimairajan, Craig Erker, Stéphanie Vairy, Lynette Bowes, Adam Fleming, Donna Johnston, Sarah McKillop, Roona Sinha, Julie Bennett, Christina Coleman, Laura Wheaton, Shayna Zelcer, Samuele Renzi, Thai Hoa Tran   +17 more
wiley   +1 more source

A bridge between influence models and control methods

Applied Network Science
Understanding how influence is seeded and spreads through social networks is an increasingly important study area. While there are many methods to identify seed nodes that are used to initialize a spread of influence, the idea of using methods for ...
Abida Sadaf, Luke Mathieson, Piotr Bródka, Katarzyna Musial   +3 more
doaj   +1 more source

Change points of global temperature

Environmental Research Letters, 2015
We aim to address the question of whether or not there is a significant recent ‘hiatus’, ‘pause’ or ‘slowdown’ of global temperature rise. Using a statistical technique known as change point (CP) analysis we identify the changes in four global ...
Niamh Cahill, Stefan Rahmstorf, Andrew C Parnell   +2 more
doaj   +1 more source

Inferring Networks of Interdependent Labor Skills to Illuminate Urban Economic Structure

Entropy, 2020
Cities are among the best examples of complex systems. The adaptive components of a city, such as its people, firms, institutions, and physical structures, form intricate and often non-intuitive interdependencies with one another. These interdependencies
Shade T. Shutters, Keith Waters
doaj   +1 more source

Comparative Drug Response Profiling in Neuroblastoma Cell Lines and Patient‐Derived Tumor Organoids

Pediatric Blood &Cancer, EarlyView.
ABSTRACT High‐risk neuroblastoma remains a leading cause of pediatric cancer mortality, and improved preclinical models are needed to guide therapeutic developments. We screened seven high‐risk neuroblastoma cell lines and three patient‐derived tumor organoids with 528 compounds alongside bone marrow controls, and compared them with external datasets ...
Krzysztof Wierbiłowicz, Se Whee Sammy Park, Aironas Los, Ernest Liu, Nona Struyf, Tom Erkers, Sören Lehmann, Jan J. Molenaar, Jakob Stenman, Olli Kallioniemi, Päivi Östling, Brinton Seashore‐Ludlow, Kasper Karlsson   +12 more
wiley   +1 more source