Results 81 to 90 of about 80,293 (261)

Cardiovascular Toxicity Associated With Bispecific Antibodies in Hematological Malignancies: A Comprehensive Pharmacovigilance Analysis

American Journal of Hematology, EarlyView.
ABSTRACT Cardiovascular adverse events (CVAEs) associated with bispecific T‐cell engaging antibodies (BsAbs) have not been systematically investigated across approved agents. In this disproportionality analysis of FAERS (December 2014–September 2025), reports listing BsAbs as the primary suspected drug (n = 7647) were compared with all other drugs in ...
Malak Munir, Ahmed Sayed, Dae Hyun Lee, Sanam Ghazi, Mustafa M. Houmsse, Saad Badat, Abdul Moeed, Avirup Guha, Daniel Addison, Narendranath Epperla   +9 more
wiley   +1 more source

Arrhythmia Management in Complex Congenital Heart Disease

JACC: Case Reports
Atrioventricular block is a common complication in L-looped single ventricles, and it may be exacerbated by palliative surgical procedures.We describe the case of a 43-year-old woman with history of double inlet left ventricle after classic Fontan procedure with subsequent Fontan revision, atrial flutter, and complete heart block managed with an ...
Mtisi, Tafadzwa, Nociti Freitas, Caio Fabio, Deeconda, Anurag, Goyal, Aditya, Malik, Aysha, Blaufox, Andrew D., Weinberg, Catherine, Averin, Konstantin, Kholwadwala, Dipak H., Tugertimur, Aykut, Saleh, Moussa Abbas, Epstein, Laurence M., Ismail, Haisam   +12 more
openaire   +2 more sources

Age‐related differences in hydroxychloroquine‐associated adverse events: A pharmacovigilance study based on the FDA Adverse Event Reporting System

British Journal of Clinical Pharmacology, EarlyView.
Aims This real‐world pharmacovigilance study utilizes FDA Adverse Event Reporting System (FAERS) data (2004–2024) to characterize age‐related disparities in hydroxychloroquine (HCQ)‐associated adverse events (AEs), addressing gaps in age‐stratified risk assessment. Methods Disproportionality analysis (reporting odds ratios, RORs) and parametric Weibull
Guanghan Sun, Jingrong Yang, Lei Wan, Xia Xu, Jing Wang   +4 more
wiley   +1 more source

Electroanatomic Contact Mapping: How to Use Optimally to Recognise the Arrhythmia Mechanism?

Indian Pacing and Electrophysiology Journal, 2010
The evolution in 3-D electroanatomic contact mapping systems has helped to considerably enhance the electrophysiologists’ understanding of real-time position management and mapping, thus to enable more precise catheter navigation within heart.
Narayanan Namboodiri
doaj  

Efficacy, safety and cost‐effectiveness of CAR‐T therapy

British Journal of Clinical Pharmacology, EarlyView.
CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher, Amina Džidić‐Krivić, Emma Pinjic, Nejra Selak, Kanita Omerbasic, Alexandar Chupin, Andrej Belancic, Almir Fajkic   +7 more
wiley   +1 more source

Exploring the early observations of parents supporting their children with school attendance problems (SAPs): A co‐produced study

British Educational Research Journal, EarlyView.
Abstract School Attendance Problems (SAPs) represent a significant challenge requiring early identification and intervention. Current service provision often does not recognise early indicators that parents observe, creating gaps between when initial concerns are raised and formal support is provided.
Tereza Aidonopoulou‐Read, Michelle Pyer, Beth Bodycote, Jackie Campbell, Kirsteen Pyer   +4 more
wiley   +1 more source

Complex ventricular arrhythmias. [PDF]

Circulation, 1981
D, Andresen, U, Tietze, E R, von Leiter, K, Wegscheider, R, Schroder   +4 more
openaire   +2 more sources

Mitochondria‐endoplasmic reticulum organelle glue as maturation promoter for origination/dimensional dual‐cross cardiomyocytes

BMEMat, EarlyView.
Mitochondria‐endoplasmic reticulum contact sites (MERCS) are areas where the mitochondria and endoplasmic reticulum closely interact. In this study, we utilize synthetic organelle glues to artificially engineer MERCS for regulating cardiomyocyte development, through which the immature and chemo‐plasticity issues of undifferentiated cells are addressed.
Wei Tang, Hao Sun, Chenqi Duan, Jiajia Chang, Yuxing Wang, Ming Zhao, Huiyue Zhao, Shan Lu, Yang Yang, Da Huo   +9 more
wiley   +1 more source

Radiofrequency Catheter Ablation of Atrioventricular Nodal Reentrant Tachycardia: It Is Not Always As It Is Expected

Indian Pacing and Electrophysiology Journal, 2004
Observation of Coincident arrhythmias is not uncommon but the co-existence of idiopathic verapamil sensitive left ventricular tachycardia (ILVT) with other arrhythmias is very rare.
Arash Arya, Majid Haghjoo, Zahra Emkanjoo, Alireza Heydari, Mohammad Ali Sadr-Ameli   +4 more
doaj  

Comparative Outcomes of Transcatheter Versus Surgical Pulmonary Valve Replacement in Adults With Congenital Heart Disease

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Pulmonary valve replacement is frequently required in adults with congenital heart disease (CHD). Comparative real‐world outcomes between percutaneous transcatheter pulmonary valve implantation (TPVR) and surgical pulmonary valve replacement (SPVR) remain incompletely characterized. We evaluated outcomes and resource utilization for
Adam Bolad, Mohamed Elganainy, Fawaz Alenezi, Issam Motairek, Islam Bolad   +4 more
wiley   +1 more source