Results 131 to 140 of about 101,253 (259)

A highly accurate Hermite polynomial-based least-squares approach for solving fractional Volterra-Fredholm integro-differential equations. [PDF]

PLoS One
Hamood MM, Sharif AA, Ghadle KP.
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

The effect of laser pulse on nonlinear thermoelasticity using an advanced analytical method. [PDF]

Sci Rep
Rabie WB, Ahmed HM, Ismail MF, Al-Ahwal A, Ramadan ME, Abdalla NSE, Ali MH.   +6 more
europepmc   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Automated Pharmacometric Model Development by Leveraging Low-Dimensional Neural ODEs and LASSO Regression. [PDF]

CPT Pharmacometrics Syst Pharmacol
Bräm DS, Steiert B, Steffens B, Pfister M, Koch G.   +4 more
europepmc   +1 more source

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

FEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson, Anja H. Schiemann, Evelyn Sattlegger   +2 more
wiley   +1 more source

Implementing physics-informed neural networks with deep learning for differential equations. [PDF]

Front Artif Intell
Emmert-Streib F, Tripathi S, Farea A, Holzinger A.   +3 more
europepmc   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Complex Boundary Value Problems of Nonlinear Differential Equations 2014

Abstract and Applied Analysis, 2014
Xinguang Zhang, Yong Hong Wu, Dragoș-Pãtru Covei, Xinan Hao   +3 more
doaj   +1 more source

Soliton solutions for the nonlinear Zoomeron equation applying the modified Khater method. [PDF]

Sci Rep
Saleem A, Abbas M, El-Rahman MA, Birhanu A, Yousaf MZ, Ahmad H.   +5 more
europepmc   +1 more source