Results 91 to 100 of about 9,536,512 (289)
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Distributed Complex Event Processing in Multiclouds [PDF]
, 2018 The last few years, the generation of vast amounts of heterogeneous data with different velocity and veracity and the requirement to process them, has significantly challenged the computational capacity and efficiency of the modern infrastructural resources. The propagation of Big Data among different processing and storage architectures, has amplified
Vassilis Stefanidis 0001 +3 more
openaire +2 more sources
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Boosting a Low-Cost Smart Home Environment with Usage and Access Control Rules
Sensors, 2018 Smart Home has gained widespread attention due to its flexible integration into everyday life. Pervasive sensing technologies are used to recognize and track the activities that people perform during the day, and to allow communication and cooperation of
Paolo Barsocchi +5 more
doaj +1 more source
A novel pattern for complex event processing in RFID applications
, 2008 This study investigates Complex Event Processing (CEP) Pattern on Radio-Frequency Identification (RFID) applications. RFID technolgy has brought tremendous benefits for the business by incorporating RFID data into supply chain planning and business ...
Zhu YL(朱云龙) +3 more
core
Towards Trustworthy Complex Event Processing
, 2014 Complex event processing has become an important technology for big data and intelligent computing because it facilitates the creation of actionable, situational knowledge from potentially large amount events in soft realtime.
Zhao, Wenbing +3 more
core +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Integration and Exploitation of Sensor Data in Smart Cities through Event-Driven Applications
Sensors, 2019 Smart cities are urban environments where Internet of Things (IoT) devices provide a continuous source of data about urban phenomena such as traffic and air pollution.
Manuel Garcia Alvarez +2 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source