Results 151 to 160 of about 43,129 (212)

Optimal Hypoxia Mimetic Small Molecules for Enhancing Angiogenic Properties of Stem Cells From Human Exfoliated Deciduous Teeth

International Endodontic Journal, EarlyView.
ABSTRACT Aim Hypoxic preconditioning of cells holds promise for regenerative therapies, yet identifying effective and safe methods for clinical application remains challenging. We aimed to determine optimal hypoxia‐mimetic small molecules (SMs) that stabilize hypoxia‐inducible factor‐1α (HIF‐1α) and their dosages for hypoxic preconditioning in stem ...
Hong Wang, Jiawei Liu, Xintao Yang, Mohamad Koohi‐Moghadam, Shuting Gao, Yuanyuan Han, Dineshi Sewvandi Thalakiriyawa, James Kit Hon Tsoi, Yanqi Yang, Waruna Lakmal Dissanayaka   +9 more
wiley   +1 more source

The Interplay of M1 Macrophages and Dental Pulp Stem Cells Promotes Angiogenesis Through IL‐8‐Dependent VEGF Regulation: An In Vitro Study

International Endodontic Journal, EarlyView.
ABSTRACT Background Dental pulp inflammation triggers immune responses involving macrophages and dental pulp stem cells (DPSCs), which interact to regulate angiogenesis essential for tissue repair. M1 pro‐inflammatory macrophages predominate early in pulpitis, and clarifying their angiogenic role is vital in identifying inflammatory regenerative ...
Dineshi Sewvandi Thalakiriyawa, Mohamad Koohi‐Moghadam, Mingxin Hu, Hong Wang, Colman McGrath, Waruna Lakmal Dissanayaka   +5 more
wiley   +1 more source

Intraoperative Agents for Hemostasis and Dural Reconstruction in Neurosurgery. [PDF]

Neurosurg Pract
Sibih YE, Haddad AF, Caldwell DJ, Aabedi AA, Yue JK.   +4 more
europepmc   +1 more source

The Biological Basis of the Merlin CP‐GEP Assay: Integrin Signaling and Early Metastatic Competence in Cutaneous Melanoma

International Journal of Dermatology, EarlyView.
Merlin CP‐GEP integrates mechanistic insights into a clinically actionable assay to predict SLN metastasis risk and inform personalized management of cutaneous melanoma. ABSTRACT The recent inclusion of the Merlin clinicopathologic–gene expression profile (CP‐GEP) assay in the National Comprehensive Cancer Network (NCCN) Melanoma Guidelines represents ...
Frank Z. Jing, Alexander Meves
wiley   +1 more source

Advances and Challenges in Tissue Engineering: Biomaterials, Cellular Strategies, and Clinical Applications. [PDF]

J Funct Biomater
Farjaminejad R, Farjaminejad S, Garcia-Godoy F, Marya A, Nucci L, Jamilian A.   +5 more
europepmc   +1 more source

Management of Non‐Plaque‐Induced Gingival Conditions: A Systematic Review—Part 2: Inflammatory and Immune Conditions; Neoplasms; and Gingival Pigmentation

Journal of Clinical Periodontology, EarlyView.
ABSTRACT Aims This systematic review assesses current evidence on the management of non‐plaque (dental biofilm)‐induced gingival diseases and conditions (NPIGDs), including (i) inflammatory and immune conditions, (ii) neoplasms and (iii) gingival pigmentations.
Maria Clotilde Carra, Cecile Wasielewski, Bruno Špiljak, Maja Sabalić‐Schoener, Sebastien Jungo, Ivan Alajbeg   +5 more
wiley   +1 more source

Local Hemostasis as the Critical Enabler for Safe Antithrombotic Therapy in Dentistry-Navigating Future Frontiers and Innovative Concepts. [PDF]

J Clin Med
Tatarciuc D, Trandafirescu MF, Ghica DC, Foia I, Armencia AO, Gradinaru I, Antohe ME, Burlea LS, Esanu IM, Vasluianu RI.   +9 more
europepmc   +1 more source

Wound Healing Patterns of PRF and PRGF Versus a Collagen‐Based Substitute and Spontaneous Healing—A Randomised Controlled Clinical Trial Assessing Wound Closure of an Experimental, Standardised Palatal Defect

Journal of Clinical Periodontology, EarlyView.
ABSTRACT Aims To evaluate wound‐healing progression among platelet‐rich fibrin (PRF), plasma rich in growth factors (PRGF), a collagen‐based wound dressing (CS = collagen substitute) and spontaneous healing (control), assessed by percentage of remaining open wound area and patient‐reported pain.
Stefan P. Bienz, Anne C. Fischer, Leonardo Mancini, Franz J. Strauss, Raphael M. Ferrari, Sonja Hitz, Ronald E. Jung, Daniel S. Thoma   +7 more
wiley   +1 more source

Plasminogen Activator Inhibitor-1 as a Therapeutic Target for Healthy Longevity, Immunosenescence, and Age-Related Disease: Translational Development of the Small-Molecule Inhibitor TM5614. [PDF]

Cells
Abdelhakim M, Miyata T.
europepmc   +1 more source

Use of Platelet‐Rich Fibrin (PRF) on Palatal Wound Healing: A Narrative Review With Clinical Recommendations

Journal of Periodontal Research, EarlyView.
Based on the available evidence, the application of platelet‐rich fibrin (PRF) following free gingival graft (FGG) and subepithelial connective tissue graft (SCTG) harvesting appears to be a promising approach for enhancing wound healing, minimizing postoperative complications, and reducing analgesic consumption. ABSTRACT This clinical narrative review
Nima Farshidfar, Paras Ahmad, Nathan Estrin, Yufeng Zhang, Richard J. Miron   +4 more
wiley   +1 more source