Results 1 to 10 of about 937,239 (252)

CVD-associated SNPs with regulatory potential reveal novel non-coding disease genes

Human Genomics, 2023
Background Cardiovascular diseases (CVDs) are the leading cause of death worldwide. Genome-wide association studies (GWAS) have identified many single nucleotide polymorphisms (SNPs) appearing in non-coding genomic regions in CVDs.
Chaonan Zhu, Nina Baumgarten, Meiqian Wu, Yue Wang, Arka Provo Das, Jaskiran Kaur, Fatemeh Behjati Ardakani, Thanh Thuy Duong, Minh Duc Pham, Maria Duda, Stefanie Dimmeler, Ting Yuan, Marcel H. Schulz, Jaya Krishnan   +13 more
doaj   +1 more source

The adipokine Retnla deficiency increases responsiveness to cardiac repair through adiponectin-rich bone marrow cells

Cell Death and Disease, 2021
Resistin-like alpha (Retnla) is a member of the resistin family and known to modulate fibrosis and inflammation. Here, we investigated the role of Retnla in the cardiac injury model.
Yong Sook Kim, Hyang Hee Cho, Dong Im Cho, Hye-yun Jeong, Soo yeon Lim, Ju Hee Jun, Mi Ra Kim, Bo Gyeong Kang, Meeyoung Cho, Hye-jin Kang, Wan Seok Kang, Goo Taeg Oh, Youngkeun Ahn   +12 more
doaj   +1 more source

Differential regulation of the water channel protein aquaporins in chondrocytes of human knee articular cartilage by aging

Scientific Reports, 2021
Knee cartilage is in an aqueous environment filled with synovial fluid consisting of water, various nutrients, and ions to maintain chondrocyte homeostasis.
Bong Soo Kyung, Koo Whang Jung, Woo Jin Yeo, Hye Kyung Seo, Yong-Soo Lee, Dong Won Suh   +5 more
doaj   +1 more source

Improving the regenerative potential of olfactory ensheathing cells by overexpressing prostacyclin synthetase and its application in spinal cord repair

Journal of Biomedical Science, 2017
Background Olfactory ensheathing cells (OEC), specialized glia that ensheathe bundles of olfactory nerves, have been reported as a favorable substrate for axonal regeneration.
May-Jywan Tsai, Chi-Ting Huang, Yong-San Huang, Ching-Feng Weng, Song-Kun Shyue, Ming-Chao Huang, Dann-Ying Liou, Yan-Ru Lin, Chu-Hsun Cheng, Huai-Sheng Kuo, Yilo Lin, Meng-Jen Lee, Wen-Hung Huang, Wen-Cheng Huang, Henrich Cheng   +14 more
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Introduction: On the Cold Edge: Environment, Art, Culture and the Arctic Circle

Regeneration
A multimodal collaboration between artists, writers, and scholars. This piece emerged from an expedition to the Arctic archipelago as part of the Arctic Circle Residency in Autumn 2022.
Candace N Jensen, Hester Blum, Jacinda Russell   +2 more
doaj   +2 more sources

Treadmill exercise modulates the medial prefrontal-amygdala neural circuit to improve the resilience against chronic restraint stress

Communications Biology, 2023
Aerobic exercise effectively ameliorates mental disorders including anxiety and depression. Current findings mainly attribute its neural mechanism to the improvement of adult neurogenesis, while leaving the possible circuitry mechanism unclear.
Zhihua Luo, Junlin Chen, Yelin Dai, Kwok-Fai So, Li Zhang   +4 more
doaj   +1 more source

Heroism

Regeneration
A multimodal collaboration between artists, writers, and scholars. This piece emerged from an expedition to the Arctic archipelago as part of the Arctic Circle Residency in Autumn 2022.
Andrea Legge, Hannah Larrabee, Harley Cowan, Jessica Creane   +3 more
doaj   +2 more sources

Unalienating Carbon: Affect and Labour in Artisanal Carbon Removal Work

Regeneration
Carbon is rapidly undergoing a joint technological and cultural transformation. With the prolific rise of carbon dioxide removal in the climate pathways and net zero commitments that contour wider energy transitions, carbon emissions are increasingly ...
Anne Pasek
doaj   +2 more sources

Physical exercise mediates a cortical FMRP–mTOR pathway to improve resilience against chronic stress in adolescent mice

Translational Psychiatry, 2023
Aerobic exercise effectively relieves anxiety disorders via modulating neurogenesis and neural activity. The molecular mechanism of exercise-mediated anxiolysis, however, remains incomplete. On a chronic restrain stress (CRS) model in adolescent mice, we
Lan Yan, Mei Wang, Fengzhen Yang, Yajie Wang, Siqi Wang, Kwok-Fai So, Li Zhang   +6 more
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Afterword: Less is the New More

Regeneration
This afterword to the special issue discusses the author’s affective experiences with energy transition. The particular focus is the affective promise of electrification as a means to rupture the ecological emergency generated by today’s petroculture.
Dominic Boyer
doaj   +2 more sources