CVD-associated SNPs with regulatory potential reveal novel non-coding disease genes
Human Genomics, 2023 Background Cardiovascular diseases (CVDs) are the leading cause of death worldwide. Genome-wide association studies (GWAS) have identified many single nucleotide polymorphisms (SNPs) appearing in non-coding genomic regions in CVDs.
Chaonan Zhu +13 more
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Cell Death and Disease, 2021 Resistin-like alpha (Retnla) is a member of the resistin family and known to modulate fibrosis and inflammation. Here, we investigated the role of Retnla in the cardiac injury model.
Yong Sook Kim +12 more
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Early redox activities modulate Xenopus tail regeneration. [PDF]
, 2018 Redox state sustained by reactive oxygen species (ROS) is crucial for regeneration; however, the interplay between oxygen (O2), ROS and hypoxia-inducible factors (HIF) remains elusive.
Ferreira, Fernando +4 more
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Scientific Reports, 2021 Knee cartilage is in an aqueous environment filled with synovial fluid consisting of water, various nutrients, and ions to maintain chondrocyte homeostasis.
Bong Soo Kyung +5 more
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Development of new all-optical signal regeneration technique [PDF]
, 2017 All-optical signal regeneration have been the active research area since last decade due to evolution of nonlinear optical signal processing. Existing all-optical signal regeneration techniques are agitated in producing low Bit Error Rate (BER) of 10-10 ...
A Mohajerin-Ariaei +21 more
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Efficient β-cell regeneration by a combination of neogenesis and replication following β-cell ablation and reversal of pancreatic duct ligation. [PDF]
, 2013 Achieving efficient β-cell regeneration is a major goal of diabetes research. Previously, we found that a combination of β-cell ablation and pancreatic duct ligation led to β-cell regeneration by direct conversion from α-cells.
Hao, Ergeng +2 more
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Entering and leaving employment in deprived neighbourhoods undergoing area regeneration [PDF]
, 2018 Concentrations of worklessness have been persistent in the UK for several decades but have not been tackled effectively by policy. An individualised approach to unemployment has existed, alongside employment policies without a strong geographical ...
Kearns, Ade, Mason, Phil
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Performance study of a novel solar solid dehumidification/regeneration bed for use in buildings air conditioning systems [PDF]
, 2017 In this paper, a novel solar solid dehumidification/regeneration bed has been proposed, and its three regeneration methods, i.e., simulated solar radiation regeneration, microwave regeneration, and combined regeneration of the microwave and simulated ...
Ding, Zezhi +5 more
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Polycistronic Delivery of IL-10 and NT-3 Promotes Oligodendrocyte Myelination and Functional Recovery in a Mouse Spinal Cord Injury Model. [PDF]
, 2020 One million estimated cases of spinal cord injury (SCI) have been reported in the United States and repairing an injury has constituted a difficult clinical challenge.
Anderson, Aileen J +8 more
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The action of obestatin in skeletal muscle repair: stem cell expansion, muscle growth, and microenvironment remodeling [PDF]
, 2015 The development of therapeutic strategies for skeletal muscle diseases, such as physical injuries and myopathies, depends on the knowledge of regulatory signals that control the myogenic process. The obestatin/GPR39 system operates as an autocrine signal
ADAMO, Sergio +16 more
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