Results 81 to 90 of about 6,670,983 (235)

Mechanism and application of fibrous proteins in diabetic wound healing: a literature review

Frontiers in Endocrinology
Diabetic wounds are more complex than normal chronic wounds because of factors such as hypoxia, reduced local angiogenesis, and prolonged inflammation phase.
Lilin Yan, Lilin Yan, Yuqing Wang, Jiawei Feng, Yiming Ni, Ting Zhang, Yemin Cao, Mingmei Zhou, Mingmei Zhou, Cheng Zhao   +9 more
doaj   +1 more source

In Situ Programmable Modulation of Hydrogel Stiffness for Stage‐Adaptive Bone Regeneration

Advanced Science, EarlyView.
Near‐infrared (NIR) irradiation triggers Ca2+ release from thermoresponsive nanocarriers, enabling in situ stiffening of an adaptive hydrogel from a soft to a stiff state, thereby sequentially supporting mesenchymal stromal cell stemness and osteogenic differentiation for stage‐adaptive bone regeneration.
Yuxin Yang, Fan Yang, Lu Wang, Zongtai Li, Weichang Li, Xinchun Zhang   +5 more
wiley   +1 more source

Model systems for platelet receptor shedding

Platelets, 2017
Platelet adhesion and aggregation at sites of vascular injury are crucial for hemostasis; however, under pathological conditions, they can cause myocardial infarction and stroke.
Markus Bender, David Stegner, Bernhard Nieswandt   +2 more
doaj   +1 more source

A Metal‐Polyphenol Self‐Assembled Coated 3D Sponge With Mild Photothermal Antibacterial, Exudate‐Controlling, and Immunomodulatory Functions for Hemostasis and Chronic Wound Healing

Advanced Science, EarlyView.
A thrombin‐functionalized copper‐polydopamine nanofiber sponge integrates rapid hemostasis, mild photothermal antibacterial therapy, stimulus‐responsive Cu2+ release, chemodynamic oxidative stress, and macrophage immunomodulation. This multifunctional dressing suppresses infection, regulates inflammation, promotes angiogenesis and re‐epithelialization,
Ziwei Zhang, Feng Qin, Xiaomeng Zhang, Xueqin Shuang, Jiahua Zhou, Ming Cheng, Baicheng Lu, Mingyue Song, Yuntian Bai, Dianying Zhang, Ming Li, Yanhua Wang   +11 more
wiley   +1 more source

Integrated proteomics highlights functional activation induced by advanced-platelet rich fibrin plus (A-PRF +) in primary equine fibroblasts

Scientific Reports
Wounds are common in equine practice, and often lead to complications such as infections, delayed healing and hypertrophic scarring, which can be costly and difficult to manage.
Maria Rosaria Miranda, Chiara Montano, Valentina Golino, Mariaelena de Chiara, Chiara Del Prete, Giacomo Pepe, Davide De Biase, Tania Ciaglia, Alessia Bertamino, Pietro Campiglia, Eduardo Sommella, Vincenzo Vestuto, Maria Pia Pasolini   +12 more
doaj   +1 more source

Clinical Audit of Autologous Platelet-Rich Fibrin Matrix with Local Antibiotic Therapy for Refractory Diabetic Foot Ulcers: 12-Month Outcomes from a Single Centre

BioMed
Background/Objectives: Diabetic Foot Ulceration (DFU) is one of the most debilitating and costly complications of diabetes mellitus, representing a significant cause of morbidity, disability, and healthcare burden worldwide. Refractory non-healing ulcers
Upamanyu Nath, Iulia Valeria Rusu, Anand Pillai   +2 more
doaj   +1 more source

Leveraging Microphysiological Systems to Facilitate Neutrophil‐Based Cancer Immunotherapy

Advanced Science, EarlyView.
Microphysiological systems are emerging as powerful human‐relevant platforms for studying neutrophil biology in cancer. Current applications of spheroids, organoids, and organ‐on‐a‐chip models are reviewed, together with future opportunities in behaviorome profiling, multi‐omics integration, personalized medicine, immune crosstalk, and multi‐organ ...
Shuai Shao, Markus Isfeld Diehl, Caroline N. Jones   +2 more
wiley   +1 more source

The Antifungal Activity of a Polygalacturonic and Caprylic Acid Ointment in an In Vitro, Three-Dimensional Wound Biofilm Model

Journal of Fungi
Candida colonization and biofilms are significant contributors to impaired wound healing. Consequently, improved treatments are needed to eradicate Candida biofilms in wounds.
Bahgat Z. Gerges, Joel Rosenblatt, Y-Lan Truong, Ying Jiang, Issam I. Raad   +4 more
doaj   +1 more source

On systolic arrays for complex matrix problems

, 1989
We consider systolic arrays for matrix computations involving complex elements, and show that in certain circumstances the complex calculations can be decomposed into a number of real matrix sub-problems which can be used to good effect in reducing ...
Megson, G.M., Evans, D.J.
core   +1 more source

Review of the Molecular and Developmental Basis of Myhre Syndrome, Bench Research

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Myhre syndrome (MS) is a connective‐tissue disorder within the acromelic dysplasia spectrum. It is characterized by congenital craniofacial, skeletal, cutaneous anomalies, respiratory, cardiovascular along with intellectual disability, deafness, and progressive fibrosis.
Camille Viaut, Valerie Cormier‐Daire
wiley   +1 more source