Results 211 to 220 of about 18,185,297 (341)

A Disease-Causing Single Amino Acid Deletion in the Coiled-Coil Domain of RAD50 Impairs MRE11 Complex Functions in Yeast and Humans.

Cell Rep, 2020
Chansel-Da Cruz M, Hohl M, Ceppi I, Kermasson L, Maggiorella L, Modesti M, de Villartay JP, Ileri T, Cejka P, Petrini JHJ, Revy P.   +10 more
europepmc   +1 more source

Heterogeneous Complex Function [PDF]

Proceedings of the 2017 International Conference on Applied Mathematics, Modelling and Statistics Application (AMMSA 2017), 2017
Xuejiao Zhao, Yun Chen, Jicheng Tao
openaire   +1 more source

Structure-Function Relationships of the Mitochondrial bc1 Complex in Temperature-sensitive Mutants of the Cytochrome b Gene, Impaired in the Catalytic Center N [PDF]

, 1995
Gaël Brasseur, Jean‐Yves Coppée, Anne-Marie Colson, Paule Brivet‐Chevillotte   +3 more
openalex   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

The lens actin filament cytoskeleton: Diverse structures for complex functions. [PDF]

Exp Eye Res, 2017
Cheng C, Nowak RB, Fowler VM.
europepmc   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

An Embryonic Stem Cell-Specific NuRD Complex Functions through Interaction with WDR5. [PDF]

Stem Cell Reports, 2017
Ee LS, McCannell KN, Tang Y, Fernandes N, Hardy WR, Green MR, Chu F, Fazzio TG.   +7 more
europepmc   +1 more source

Beclin–phosphatidylinositol 3‐kinase complex functions at the trans‐Golgi network

EMBO Reports, 2001
A. Kihara, Y. Kabeya, Y. Ohsumi, T. Yoshimori   +3 more
semanticscholar   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

11th IUBMB Focused Meeting on the Aminoacyl-tRNA Synthetases: Sailing a New Sea of Complex Functions in Human Biology and Disease. [PDF]

Biomolecules, 2018
Francklyn C, Roy H, Alexander R.
europepmc   +1 more source