Results 131 to 140 of about 1,518,600 (268)

Inhibition of Complex I of the Respiratory Chain, but Not Complex III, Attenuates Degranulation and Cytokine Secretion in Human Skin Mast Cells. [PDF]

Int J Mol Sci, 2022
Buttgereit T, Pfeiffenberger M, Frischbutter S, Krauß PL, Chen Y, Maurer M, Buttgereit F, Gaber T.   +7 more
europepmc   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

Macrophage respiratory complex III governs immune evasion. [PDF]

Immunometabolism (Cobham)
Neumann MA, Frezza C.
europepmc   +1 more source

Genomic analysis of the endosomal sorting required for transport complex III pathway genes as therapeutic and prognostic biomarkers for endometrial carcinoma. [PDF]

Transl Cancer Res, 2022
Yang Y, Wang M.
europepmc   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Mitochondrial complex III subunit Qcr8 regulates the virulence and adhesion of <i>Candida albicans</i> by modulating mitochondrial function. [PDF]

Microbiol Spectr
Zhao Q, Huang X, Liu Q, Cao Y, Yu X, Liu Y, Hu N, Han Z, Tan J, Li X, Zhang Y, Wang K, Li Y, Zeng L.   +13 more
europepmc   +1 more source

Clinical and diagnostic characteristics of complex III mitopathy due to novel BCS1L gene mutation in a Saudi patient. [PDF]

BMC Med Genomics, 2022
Al Qurashi M, Mustafa A, Aga SS, Ahmad A, El-Farra A, Shawli A, Al Hindi M, Hasosah M.   +7 more
europepmc   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Dysregulation of the endosomal sorting complex III is linked to neurodegeneration in progressive multiple sclerosis. [PDF]

Brain Pathol
Picon C, Aleksynas R, Wojewska M, de Virgiliis F, Merkler D, Reynolds R.   +5 more
europepmc   +1 more source

Ovarian carcinoma immunoreactive antigen-like protein 2 (OCIAD2) is a novel complex III-specific assembly factor in mitochondria. [PDF]

Mol Biol Cell, 2022
Chojnacka KJ, Elancheliyan P, Mussulini BHM, Mohanraj K, Callegari S, Gosk A, Banach T, Góral T, Szczepanowska K, Rehling P, Serwa RA, Chacinska A.   +11 more
europepmc   +1 more source