Results 141 to 150 of about 1,518,600 (268)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Mitochondrial complex III-derived ROS amplify immunometabolic changes in astrocytes and promote dementia pathology. [PDF]

Nat Metab
Barnett D, Zimmer TS, Booraem C, Palaguachi F, Meadows SM, Xiao H, Wong MY, Luo W, Gan L, Chouchani ET, Orr AG, Orr AL.   +11 more
europepmc   +1 more source

DJ-1 attenuates the glycation of mitochondrial complex I and complex III in the post-ischemic heart. [PDF]

Sci Rep, 2021
Pantner Y, Polavarapu R, Chin LS, Li L, Shimizu Y, Calvert JW.   +5 more
europepmc   +1 more source

Mitochondrial complex III and related bc-complexes

Biochimica et Biophysica Acta (BBA) - Bioenergetics, 2013
openaire   +2 more sources

The therapeutic opportunities and pitfalls of using iron ion chelators to treat neurodegenerative diseases

FEBS Letters, EarlyView.
Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley   +1 more source

Long-Distance Charge Transport between Cytochrome c and Complex III is Mediated by Protons and Reactive Oxygen Species. [PDF]

Small
Lagunas A, Gomila AMJ, Nin-Hill A, Guerra-Castellano A, Pérez-Mejías G, Samitier J, Rovira C, la Rosa MA, Díaz-Moreno I, Gorostiza P.   +9 more
europepmc   +1 more source

Mammalian complex III heme dynamics studied with pump-probe spectroscopy and red light illuminations. [PDF]

Biomed Opt Express, 2021
O'Connor SP, Powell SM, Rickman JM, Pope NJ, Noojin GD, Scully MO, Denton ML, Yakovlev VV.   +7 more
europepmc   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Spermidine toxicity in Saccharomyces cerevisiae due to mitochondrial complex III deficiency. [PDF]

Biogerontology
Su WH, Smith JJ, Cheng E, Nishitani MS, Choi CY, Lee KR, Salzano AP, Schriner SE.   +7 more
europepmc   +1 more source

The mitochondrial carrier SFXN1 is critical for complex III integrity and cellular metabolism. [PDF]

Cell Rep, 2021
Acoba MG, Alpergin ESS, Renuse S, Fernández-Del-Río L, Lu YW, Khalimonchuk O, Clarke CF, Pandey A, Wolfgang MJ, Claypool SM.   +9 more
europepmc   +1 more source