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Envisioning clinical trials as complex interventions. [PDF]

open access: yesCancer, 2022
AbstractClinical trials are critical components of modern health care and infrastructure. Trials benefit society through scientific advancement and individual patients through trial participation. In fact, billions of dollars are spent annually in support of these benefits. Despite the massive investments, clinical trials often fail to accomplish their
Stensland KD   +4 more
europepmc   +3 more sources

From complex social interventions to interventions in complex social systems: Future directions and unresolved questions for intervention development and evaluation [PDF]

open access: yesEvaluation, 2018
Complex systems approaches to social intervention research are increasingly advocated. However, there have been few attempts to consider how models of intervention science, such as the UK’s Medical Research Council complex interventions framework, might be reframed through a complex systems lens.
Moore, Graham   +6 more
openaire   +6 more sources

Changes to coping and its relationship to improved wellbeing in the optimal health program for chronic disease

open access: yesSSM - Mental Health, 2023
Background: Adaptive-style coping strategies are associated with favourable mental health and quality of life outcomes among individuals with chronic disease.
Maya S. Sheth   +5 more
doaj   +1 more source

Incorporating gender, equity, and human rights into the action planning process: moving from rhetoric to action [PDF]

open access: yesGlobal Health Action, 2016
Background: Mainstreaming of gender, equity, and human rights (GER) is an important focus of the World Health Organization (WHO) and other UN organizations. This paper explores the role of action plans in mainstreaming GER.
Sanjeev Sridharan   +4 more
doaj   +1 more source

Contingency Management for Treatment of Cannabis Use Disorder in Co-Occurring Mental Health Disorders: A Systematic Review

open access: yesBrain Sciences, 2022
Amongst individuals with a mental health disorder, a comorbid diagnosis of cannabis use disorder (CUD) is associated with numerous adverse consequences, including more severe symptom profiles, poorer treatment response, and reduced psychosocial ...
Justyne D. Rodas   +2 more
doaj   +1 more source

The role of evaluation in iterative learning and implementation of quality of care interventions

open access: yesGlobal Health Action, 2021
Background: The Lancet Global Health Commission (LGHC) has argued that quality of care (QoC) is an emergent property that requires an iterative process to learn and implement.
Nikhil Shah   +4 more
doaj   +1 more source

A Qualitative Systematic Review of Experiences and Barriers Faced by Migrant Women with Perinatal Depression in Canada

open access: yesWomen, 2022
Perinatal depression is the onset of depressive symptoms during pregnancy and up to one year after childbirth. Migrant women are at higher risk of experiencing perinatal depression due to numerous psychosocial stressors related to their experiences. This
Gil Angela Dela Cruz   +4 more
doaj   +1 more source

Complex Cardiovascular Interventions

open access: yesJACC: Case Reports, 2019
Yiannis S. Chatzizisis, MD, PhD
doaj   +4 more sources

Where theory and practice of global health intersect: the developmental history of a Canadian global health initiative [PDF]

open access: yesGlobal Health Action, 2014
Objective: This paper examines the scope of practice of global health, drawing on the practical experience of a global health initiative of the Government of Canada – the Teasdale-Corti Global Health Research Partnership Program.
Ibrahim Daibes, Sanjeev Sridharan
doaj   +1 more source

Complex Interventions Deserve Complex Evaluations: A Transdisciplinary Approach to Evaluation of a Preventive Personalized Medicine Intervention [PDF]

open access: yesFrontiers in Public Health, 2022
Non-communicable diseases (NCDs) are the largest cause of disability and death globally. The human and financial costs of NCDs have raised questions of sustainability for many health systems. Personalized, preventive health interventions are an innovative way to address NCDs, but it is difficult to measure their effectiveness using standard evaluation ...
Elise M. Garton   +7 more
openaire   +3 more sources

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